Prevalence, correlates and outcomes of insomnia in patients with first episode psychosis from a tertiary psychiatric institution in Singapore

Mythily Subramaniam, Edimansyah Abdin, Shazana Shahwan, Pratika Satghare, Janhavi A. Vaingankar, Jagan Rama Sendren, Louisa Picco, Boon Yiang Chua, Boon Tat Ng, Siow Ann Chong, Swapna Verma

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Objectives The study aimed to evaluate the prevalence of insomnia in patients with first episode psychosis (FEP) and to explore the relationship between insomnia and socio-demographic and clinical variables as well as quality of life (QOL) and functioning in Singapore. Methods Data on sleep, smoking, alcohol habits, QOL and socio-demographics were collected from 280 FEP patients who were enrolled in the Early Psychosis Intervention Programme (EPIP) within 3 months of joining the programme. Multiple logistic regression analyses were performed to determine the socio-demographic and clinical correlates of insomnia. The association of insomnia with QOL as well as functioning was examined using multiple linear regression analyses. Results The prevalence of clinical insomnia was 22.6%. Older age and higher dosage of antipsychotic medication were significantly associated with a lower risk of insomnia while hazardous alcohol use, current smoking and a longer duration of untreated psychosis were significantly associated with a higher risk of insomnia. Insomnia was associated with significant decreases in all QOL domains assessed in the study even after adjusting for confounders. Conclusions FEP patients with insomnia must be screened for hazardous alcohol use and smoking. Patients must be referred concurrently for treatment of insomnia, smoking cessation as well as brief intervention for hazardous alcohol use when needed.

Original languageEnglish
Pages (from-to)15-21
Number of pages7
JournalGeneral Hospital Psychiatry
Publication statusPublished - 1 Mar 2018
Externally publishedYes


  • Anti-psychotics
  • First-episode psychosis
  • Hazardous alcohol use
  • Singapore
  • Smoking

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