TY - JOUR
T1 - Prevalence, correlates and outcomes of insomnia in patients with first episode psychosis from a tertiary psychiatric institution in Singapore
AU - Subramaniam, Mythily
AU - Abdin, Edimansyah
AU - Shahwan, Shazana
AU - Satghare, Pratika
AU - Vaingankar, Janhavi A.
AU - Rama Sendren, Jagan
AU - Picco, Louisa
AU - Chua, Boon Yiang
AU - Ng, Boon Tat
AU - Chong, Siow Ann
AU - Verma, Swapna
PY - 2018/3/1
Y1 - 2018/3/1
N2 - Objectives The study aimed to evaluate the prevalence of insomnia in patients with first episode psychosis (FEP) and to explore the relationship between insomnia and socio-demographic and clinical variables as well as quality of life (QOL) and functioning in Singapore. Methods Data on sleep, smoking, alcohol habits, QOL and socio-demographics were collected from 280 FEP patients who were enrolled in the Early Psychosis Intervention Programme (EPIP) within 3 months of joining the programme. Multiple logistic regression analyses were performed to determine the socio-demographic and clinical correlates of insomnia. The association of insomnia with QOL as well as functioning was examined using multiple linear regression analyses. Results The prevalence of clinical insomnia was 22.6%. Older age and higher dosage of antipsychotic medication were significantly associated with a lower risk of insomnia while hazardous alcohol use, current smoking and a longer duration of untreated psychosis were significantly associated with a higher risk of insomnia. Insomnia was associated with significant decreases in all QOL domains assessed in the study even after adjusting for confounders. Conclusions FEP patients with insomnia must be screened for hazardous alcohol use and smoking. Patients must be referred concurrently for treatment of insomnia, smoking cessation as well as brief intervention for hazardous alcohol use when needed.
AB - Objectives The study aimed to evaluate the prevalence of insomnia in patients with first episode psychosis (FEP) and to explore the relationship between insomnia and socio-demographic and clinical variables as well as quality of life (QOL) and functioning in Singapore. Methods Data on sleep, smoking, alcohol habits, QOL and socio-demographics were collected from 280 FEP patients who were enrolled in the Early Psychosis Intervention Programme (EPIP) within 3 months of joining the programme. Multiple logistic regression analyses were performed to determine the socio-demographic and clinical correlates of insomnia. The association of insomnia with QOL as well as functioning was examined using multiple linear regression analyses. Results The prevalence of clinical insomnia was 22.6%. Older age and higher dosage of antipsychotic medication were significantly associated with a lower risk of insomnia while hazardous alcohol use, current smoking and a longer duration of untreated psychosis were significantly associated with a higher risk of insomnia. Insomnia was associated with significant decreases in all QOL domains assessed in the study even after adjusting for confounders. Conclusions FEP patients with insomnia must be screened for hazardous alcohol use and smoking. Patients must be referred concurrently for treatment of insomnia, smoking cessation as well as brief intervention for hazardous alcohol use when needed.
KW - Anti-psychotics
KW - First-episode psychosis
KW - Hazardous alcohol use
KW - Singapore
KW - Smoking
UR - http://www.scopus.com/inward/record.url?scp=85038256107&partnerID=8YFLogxK
U2 - 10.1016/j.genhosppsych.2017.11.009
DO - 10.1016/j.genhosppsych.2017.11.009
M3 - Article
C2 - 29268166
AN - SCOPUS:85038256107
VL - 51
SP - 15
EP - 21
JO - General Hospital Psychiatry
JF - General Hospital Psychiatry
SN - 0163-8343
ER -