Prevalence and Antimicrobial Resistance of Mycoplasma genitalium Infection among Women Living with Human Immunodeficiency Virus in South Africa

A Prospective Cohort Study

Jason J. Ong, Mahlape Precious Magooa, Admire Chikandiwa, Helen Kelly, Marie Noelle Didelot, Etienne E. Muller, Venessa Maseko, Michel Segondy, Sinead Delany-Moretlwe, Ranmini Kularatne, Philippe Mayaud, on behalf of the HIV in Africa Research Partnership Study Group

Research output: Contribution to journalArticleResearchpeer-review

Abstract

This prospective cohort study of 622 women living with human immunodeficiency virus (HIV) from Johannesburg (2012) detected Mycoplasma genitalium in 7.4% (95% confidence interval [CI]: 5.5-9.7, 46/622), with detection more likely with lower CD4 counts(adjusted odds ratio [AOR] 1.02 per 10 cells/μL decrease, 95% CI: 1.00-1.03) and higher plasma HIV-1 RNA (AOR 1.15 per log copies/mL increase, 95% CI: 1.03-1.27). No mutations for macrolide/quinolone resistance was detected.

Original languageEnglish
Pages (from-to)873-876
Number of pages4
JournalClinical Infectious Diseases
Volume69
Issue number5
DOIs
Publication statusPublished - 16 Aug 2019

Keywords

  • antimicrobial resistance
  • HIV
  • Mycoplasma genitalium
  • sexually transmitted infections
  • women

Cite this

Ong, J. J., Magooa, M. P., Chikandiwa, A., Kelly, H., Didelot, M. N., Muller, E. E., ... on behalf of the HIV in Africa Research Partnership Study Group (2019). Prevalence and Antimicrobial Resistance of Mycoplasma genitalium Infection among Women Living with Human Immunodeficiency Virus in South Africa: A Prospective Cohort Study. Clinical Infectious Diseases, 69(5), 873-876. https://doi.org/10.1093/cid/ciz045
Ong, Jason J. ; Magooa, Mahlape Precious ; Chikandiwa, Admire ; Kelly, Helen ; Didelot, Marie Noelle ; Muller, Etienne E. ; Maseko, Venessa ; Segondy, Michel ; Delany-Moretlwe, Sinead ; Kularatne, Ranmini ; Mayaud, Philippe ; on behalf of the HIV in Africa Research Partnership Study Group. / Prevalence and Antimicrobial Resistance of Mycoplasma genitalium Infection among Women Living with Human Immunodeficiency Virus in South Africa : A Prospective Cohort Study. In: Clinical Infectious Diseases. 2019 ; Vol. 69, No. 5. pp. 873-876.
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abstract = "This prospective cohort study of 622 women living with human immunodeficiency virus (HIV) from Johannesburg (2012) detected Mycoplasma genitalium in 7.4{\%} (95{\%} confidence interval [CI]: 5.5-9.7, 46/622), with detection more likely with lower CD4 counts(adjusted odds ratio [AOR] 1.02 per 10 cells/μL decrease, 95{\%} CI: 1.00-1.03) and higher plasma HIV-1 RNA (AOR 1.15 per log copies/mL increase, 95{\%} CI: 1.03-1.27). No mutations for macrolide/quinolone resistance was detected.",
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author = "Ong, {Jason J.} and Magooa, {Mahlape Precious} and Admire Chikandiwa and Helen Kelly and Didelot, {Marie Noelle} and Muller, {Etienne E.} and Venessa Maseko and Michel Segondy and Sinead Delany-Moretlwe and Ranmini Kularatne and Philippe Mayaud and {on behalf of the HIV in Africa Research Partnership Study Group}",
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Ong, JJ, Magooa, MP, Chikandiwa, A, Kelly, H, Didelot, MN, Muller, EE, Maseko, V, Segondy, M, Delany-Moretlwe, S, Kularatne, R, Mayaud, P & on behalf of the HIV in Africa Research Partnership Study Group 2019, 'Prevalence and Antimicrobial Resistance of Mycoplasma genitalium Infection among Women Living with Human Immunodeficiency Virus in South Africa: A Prospective Cohort Study', Clinical Infectious Diseases, vol. 69, no. 5, pp. 873-876. https://doi.org/10.1093/cid/ciz045

Prevalence and Antimicrobial Resistance of Mycoplasma genitalium Infection among Women Living with Human Immunodeficiency Virus in South Africa : A Prospective Cohort Study. / Ong, Jason J.; Magooa, Mahlape Precious; Chikandiwa, Admire; Kelly, Helen; Didelot, Marie Noelle; Muller, Etienne E.; Maseko, Venessa; Segondy, Michel; Delany-Moretlwe, Sinead; Kularatne, Ranmini; Mayaud, Philippe; on behalf of the HIV in Africa Research Partnership Study Group.

In: Clinical Infectious Diseases, Vol. 69, No. 5, 16.08.2019, p. 873-876.

Research output: Contribution to journalArticleResearchpeer-review

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