Prevalence and Antimicrobial Resistance of Mycoplasma genitalium Infection among Women Living with Human Immunodeficiency Virus in South Africa: A Prospective Cohort Study

Jason J. Ong, Mahlape Precious Magooa, Admire Chikandiwa, Helen Kelly, Marie Noelle Didelot, Etienne E. Muller, Venessa Maseko, Michel Segondy, Sinead Delany-Moretlwe, Ranmini Kularatne, Philippe Mayaud, on behalf of the HIV in Africa Research Partnership Study Group

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Abstract

This prospective cohort study of 622 women living with human immunodeficiency virus (HIV) from Johannesburg (2012) detected Mycoplasma genitalium in 7.4% (95% confidence interval [CI]: 5.5-9.7, 46/622), with detection more likely with lower CD4 counts(adjusted odds ratio [AOR] 1.02 per 10 cells/μL decrease, 95% CI: 1.00-1.03) and higher plasma HIV-1 RNA (AOR 1.15 per log copies/mL increase, 95% CI: 1.03-1.27). No mutations for macrolide/quinolone resistance was detected.

Original languageEnglish
Pages (from-to)873-876
Number of pages4
JournalClinical Infectious Diseases
Volume69
Issue number5
DOIs
Publication statusPublished - 16 Aug 2019

Keywords

  • antimicrobial resistance
  • HIV
  • Mycoplasma genitalium
  • sexually transmitted infections
  • women

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