Preterm infants exhibit greater variability in cerebrovascular control than term infants

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Sudden Infant Death Syndrome (SIDS) remains an important cause of infant death, particularly amongst infants born preterm. Prone sleeping is the major risk factor for SIDS and this has recently been shown to alter cerebrovascular control in term infants. As preterm infants are at greater risk for SIDS than those born at term, we hypothesized that their cerebrovascular control in the prone position would be reduced compared to term infants. Patients or Participants: 35 preterm (mean gestation 31.2?0.4wk) and 17 term (mean gestation 40.1?0.3wk) infants. Design: Infants underwent daytime polysomnography at 2-4 weeks, 2-3 months and 5-6 months post-term age. Infants slept both prone and supine and were presented with cardiovascular challenges in the form of 15? head-up tilts (HUT). Measurements and Results: Cerebral tissue oxygenation index (TOI) was recorded using near-infrared spectroscopy (NIRO-200 spectrophotometer, Hamamatsu Photonics KK, Japan) and mean arterial pressure (MAP) was recorded using a FinometerTM cuff (Finapress Medical Systems, Amsterdam, The Netherlands). In the prone position TOI increased following the HUT (P
Original languageEnglish
Pages (from-to)1411 - 1421
Number of pages11
JournalSleep
Volume38
Issue number9
DOIs
Publication statusPublished - 2015

Cite this

@article{0b065a36203148a48317edaf055552a8,
title = "Preterm infants exhibit greater variability in cerebrovascular control than term infants",
abstract = "Sudden Infant Death Syndrome (SIDS) remains an important cause of infant death, particularly amongst infants born preterm. Prone sleeping is the major risk factor for SIDS and this has recently been shown to alter cerebrovascular control in term infants. As preterm infants are at greater risk for SIDS than those born at term, we hypothesized that their cerebrovascular control in the prone position would be reduced compared to term infants. Patients or Participants: 35 preterm (mean gestation 31.2?0.4wk) and 17 term (mean gestation 40.1?0.3wk) infants. Design: Infants underwent daytime polysomnography at 2-4 weeks, 2-3 months and 5-6 months post-term age. Infants slept both prone and supine and were presented with cardiovascular challenges in the form of 15? head-up tilts (HUT). Measurements and Results: Cerebral tissue oxygenation index (TOI) was recorded using near-infrared spectroscopy (NIRO-200 spectrophotometer, Hamamatsu Photonics KK, Japan) and mean arterial pressure (MAP) was recorded using a FinometerTM cuff (Finapress Medical Systems, Amsterdam, The Netherlands). In the prone position TOI increased following the HUT (P",
author = "Karinna Fyfe and Alexsandria Odoi and Stephanie Yiallourou and Wong, {Flora Yuen-Wait} and Walker, {Adrian Mark} and Horne, {Rosemary Sylvia Claire}",
year = "2015",
doi = "10.5665/sleep.4980",
language = "English",
volume = "38",
pages = "1411 -- 1421",
journal = "Sleep",
issn = "0161-8105",
publisher = "Associated Professional Sleep Societies",
number = "9",

}

Preterm infants exhibit greater variability in cerebrovascular control than term infants. / Fyfe, Karinna; Odoi, Alexsandria; Yiallourou, Stephanie; Wong, Flora Yuen-Wait; Walker, Adrian Mark; Horne, Rosemary Sylvia Claire.

In: Sleep, Vol. 38, No. 9, 2015, p. 1411 - 1421.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Preterm infants exhibit greater variability in cerebrovascular control than term infants

AU - Fyfe, Karinna

AU - Odoi, Alexsandria

AU - Yiallourou, Stephanie

AU - Wong, Flora Yuen-Wait

AU - Walker, Adrian Mark

AU - Horne, Rosemary Sylvia Claire

PY - 2015

Y1 - 2015

N2 - Sudden Infant Death Syndrome (SIDS) remains an important cause of infant death, particularly amongst infants born preterm. Prone sleeping is the major risk factor for SIDS and this has recently been shown to alter cerebrovascular control in term infants. As preterm infants are at greater risk for SIDS than those born at term, we hypothesized that their cerebrovascular control in the prone position would be reduced compared to term infants. Patients or Participants: 35 preterm (mean gestation 31.2?0.4wk) and 17 term (mean gestation 40.1?0.3wk) infants. Design: Infants underwent daytime polysomnography at 2-4 weeks, 2-3 months and 5-6 months post-term age. Infants slept both prone and supine and were presented with cardiovascular challenges in the form of 15? head-up tilts (HUT). Measurements and Results: Cerebral tissue oxygenation index (TOI) was recorded using near-infrared spectroscopy (NIRO-200 spectrophotometer, Hamamatsu Photonics KK, Japan) and mean arterial pressure (MAP) was recorded using a FinometerTM cuff (Finapress Medical Systems, Amsterdam, The Netherlands). In the prone position TOI increased following the HUT (P

AB - Sudden Infant Death Syndrome (SIDS) remains an important cause of infant death, particularly amongst infants born preterm. Prone sleeping is the major risk factor for SIDS and this has recently been shown to alter cerebrovascular control in term infants. As preterm infants are at greater risk for SIDS than those born at term, we hypothesized that their cerebrovascular control in the prone position would be reduced compared to term infants. Patients or Participants: 35 preterm (mean gestation 31.2?0.4wk) and 17 term (mean gestation 40.1?0.3wk) infants. Design: Infants underwent daytime polysomnography at 2-4 weeks, 2-3 months and 5-6 months post-term age. Infants slept both prone and supine and were presented with cardiovascular challenges in the form of 15? head-up tilts (HUT). Measurements and Results: Cerebral tissue oxygenation index (TOI) was recorded using near-infrared spectroscopy (NIRO-200 spectrophotometer, Hamamatsu Photonics KK, Japan) and mean arterial pressure (MAP) was recorded using a FinometerTM cuff (Finapress Medical Systems, Amsterdam, The Netherlands). In the prone position TOI increased following the HUT (P

UR - http://www.ncbi.nlm.nih.gov/pubmed/25669192

U2 - 10.5665/sleep.4980

DO - 10.5665/sleep.4980

M3 - Article

VL - 38

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EP - 1421

JO - Sleep

JF - Sleep

SN - 0161-8105

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