Pressure pain threshold in pain‐free subjects, in patients with chronic regional pain syndromes, and in patients with fibromyalgia syndrome

Gerald Granges, Geoffrey Littlejohn

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236 Citations (Scopus)


Objective. We hypothesized that change in pain threshold to pressure reflects a generalized change in the pain system affecting both tender and control points. Methods. We assessed 18 tender points and 4 control points using an algometer in 60 patients with generalized fibromyalgia/fibrositis syndrome, 60 patients with localized chronic pain syndromes, and in 60 pain‐free subjects. Results. A significant correlation was found between myalgia scores at tender points and control points in these subjects. Conclusion. These results suggest that there is a diffuse change in pain modulation in fibromyalgia, as hypothesized, but the tender point is still clinically useful.

Original languageEnglish
Pages (from-to)642-646
Number of pages5
JournalArthritis and Rheumatism
Issue number5
Publication statusPublished - 1 Jan 1993
Externally publishedYes

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