Presence of antibodies to human immunodeficiency virus-1 in reference reagents of human origin in diagnostic kits

F. A. Brake, W. J. Maskill, T. S. Howard, A. M. Breschkin, S. S. Gandhi

Research output: Contribution to journalArticleResearchpeer-review

Abstract

We tested 54 reagents of human origin that were included in a number of diagnostic kits to be used as positive or negative control material, and for quality assurance, for the presence of antibodies to human immunodeficiency virus-1 (HIV-1). Of these, 12 (22%) reagents were found to give positive results for antibodies to HIV-1 by enzyme-linked immunosorbent assay and/or supplementary tests. These results suggest that some diagnostic reagents of human origin may be contaminated with HIV-1 and potentially may be infectious.

Original languageEnglish
Pages (from-to)503-505
Number of pages3
JournalMedical Journal of Australia
Volume148
Issue number10
Publication statusPublished - 1 Jan 1988
Externally publishedYes

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