Prescribing for older people with chronic renal impairment

J Simon Bell; Natalie Blacker; V. Tammy LeBlanc; Christopher P. Alderman; Adam Phillips; Debra Rowett; Simone Rossi; Oliver Frank; Alan J Husband

Prescribing for older people with chronic renal impairment

J Simon Bell, Natalie Blacker, V. Tammy LeBlanc, Christopher P. Alderman, Adam Phillips, Debra Rowett, Simone Rossi, Oliver Frank, Alan J Husband

Research output: Contribution to journal › Article › Research › peer-review

20 Citations (Scopus)

Abstract

Background: Renal function is an important prescribing consideration. On average, glomerular filtration rate declines by about 10 mL/min every 10 years after the age of 40. Renal impairment may cause medicines to accumulate or cause toxicity, especially if the medicine has a narrow therapeutic index.

Objective: To present an overview of prescribing considerations in the primary care setting for patients with chronic renal impairment.

Discussion: Serum creatinine considered in isolation is not a reliable indicator of renal function. The estimated glomerular filtration rate provided in pathology reporting can alert prescribers to possible renal impairment and the need to consider dose adjustments. The Cockcroft-Gault equation should be used to adjust medicine doses. Renal function monitoring is recommended for patients using medicines that can impair renal function or cause nephrotoxicity (eg. NSAIDs, ACEIs, ARBs).

Original language	English
Pages (from-to)	24-28
Number of pages	5
Journal	Australian Family Physician
Volume	42
Issue number	1
Publication status	Published - Jan 2013
Externally published	Yes

Keywords

Aged
Pharmaceutical preparations/ administration and dosage
Renal insufficiency

Access to Document

Cite this

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title = "Prescribing for older people with chronic renal impairment",

abstract = "Background: Renal function is an important prescribing consideration. On average, glomerular filtration rate declines by about 10 mL/min every 10 years after the age of 40. Renal impairment may cause medicines to accumulate or cause toxicity, especially if the medicine has a narrow therapeutic index. Objective: To present an overview of prescribing considerations in the primary care setting for patients with chronic renal impairment. Discussion: Serum creatinine considered in isolation is not a reliable indicator of renal function. The estimated glomerular filtration rate provided in pathology reporting can alert prescribers to possible renal impairment and the need to consider dose adjustments. The Cockcroft-Gault equation should be used to adjust medicine doses. Renal function monitoring is recommended for patients using medicines that can impair renal function or cause nephrotoxicity (eg. NSAIDs, ACEIs, ARBs).",

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T1 - Prescribing for older people with chronic renal impairment

AU - Bell, J Simon

AU - Blacker, Natalie

AU - LeBlanc, V. Tammy

AU - Alderman, Christopher P.

AU - Phillips, Adam

AU - Rowett, Debra

AU - Rossi, Simone

AU - Frank, Oliver

AU - Husband, Alan J

PY - 2013/1

Y1 - 2013/1

N2 - Background: Renal function is an important prescribing consideration. On average, glomerular filtration rate declines by about 10 mL/min every 10 years after the age of 40. Renal impairment may cause medicines to accumulate or cause toxicity, especially if the medicine has a narrow therapeutic index. Objective: To present an overview of prescribing considerations in the primary care setting for patients with chronic renal impairment. Discussion: Serum creatinine considered in isolation is not a reliable indicator of renal function. The estimated glomerular filtration rate provided in pathology reporting can alert prescribers to possible renal impairment and the need to consider dose adjustments. The Cockcroft-Gault equation should be used to adjust medicine doses. Renal function monitoring is recommended for patients using medicines that can impair renal function or cause nephrotoxicity (eg. NSAIDs, ACEIs, ARBs).

AB - Background: Renal function is an important prescribing consideration. On average, glomerular filtration rate declines by about 10 mL/min every 10 years after the age of 40. Renal impairment may cause medicines to accumulate or cause toxicity, especially if the medicine has a narrow therapeutic index. Objective: To present an overview of prescribing considerations in the primary care setting for patients with chronic renal impairment. Discussion: Serum creatinine considered in isolation is not a reliable indicator of renal function. The estimated glomerular filtration rate provided in pathology reporting can alert prescribers to possible renal impairment and the need to consider dose adjustments. The Cockcroft-Gault equation should be used to adjust medicine doses. Renal function monitoring is recommended for patients using medicines that can impair renal function or cause nephrotoxicity (eg. NSAIDs, ACEIs, ARBs).

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KW - Pharmaceutical preparations/ administration and dosage

KW - Renal insufficiency

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