Preparation and evaluation of biopolymeric nanoparticles encapsulating green tea catechins

Admire Dube; Ian Clair Larson

Preparation and evaluation of biopolymeric nanoparticles encapsulating green tea catechins

Drug Delivery Disposition & Dynamics

Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › Research › peer-review

Abstract

Chitosan-tripolyphosphate and chitosan-alginate nanoparticles encapsulating (+)-catechin have been prepared and characterized. Using a novel method to evaluate the stability of the catechin within the nanoparticles, we found that the nanoparticles protect (+)- catechin from oxidative degradation in simulated intestinal fluids. In-vitro release studies demonstrated a pH dependent release of the catechin. These nanoparticles are therefore promising delivery systems to improve the oral bioavailability.

Original language	English
Title of host publication	36th Annual Meeting & Exposition of the Controlled Release Society
Editors	Evidence of peer review attached
Place of Publication	USA
Publisher	Controlled Release Society
Pages	on cd - on cd
Number of pages	2
ISBN (Print)	9781615675418
Publication status	Published - 2009
Event	Annual Meeting & Exposition of the Controlled Release Society 2009 - Bella Center Coppenhagen Denmark, USA Duration: 1 Jan 2009 → …

Conference

Conference	Annual Meeting & Exposition of the Controlled Release Society 2009
City	USA
Period	1/01/09 → …

Cite this

@inproceedings{24a4ffa9300948109beaa06af78aae87,

title = "Preparation and evaluation of biopolymeric nanoparticles encapsulating green tea catechins",

abstract = "Chitosan-tripolyphosphate and chitosan-alginate nanoparticles encapsulating (+)-catechin have been prepared and characterized. Using a novel method to evaluate the stability of the catechin within the nanoparticles, we found that the nanoparticles protect (+)- catechin from oxidative degradation in simulated intestinal fluids. In-vitro release studies demonstrated a pH dependent release of the catechin. These nanoparticles are therefore promising delivery systems to improve the oral bioavailability.",

author = "Admire Dube and Larson, \{Ian Clair\}",

year = "2009",

language = "English",

isbn = "9781615675418",

pages = "on cd -- on cd",

editor = "\{Evidence of peer review attached\}",

booktitle = "36th Annual Meeting \& Exposition of the Controlled Release Society",

publisher = "Controlled Release Society",

address = "United States of America",

note = "Annual Meeting \& Exposition of the Controlled Release Society 2009 ; Conference date: 01-01-2009",

}

Preparation and evaluation of biopolymeric nanoparticles encapsulating green tea catechins. / Dube, Admire; Larson, Ian Clair.
36th Annual Meeting & Exposition of the Controlled Release Society. ed. / Evidence of peer review attached. USA: Controlled Release Society, 2009. p. on cd - on cd.

Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › Research › peer-review

TY - GEN

T1 - Preparation and evaluation of biopolymeric nanoparticles encapsulating green tea catechins

AU - Dube, Admire

AU - Larson, Ian Clair

PY - 2009

Y1 - 2009

N2 - Chitosan-tripolyphosphate and chitosan-alginate nanoparticles encapsulating (+)-catechin have been prepared and characterized. Using a novel method to evaluate the stability of the catechin within the nanoparticles, we found that the nanoparticles protect (+)- catechin from oxidative degradation in simulated intestinal fluids. In-vitro release studies demonstrated a pH dependent release of the catechin. These nanoparticles are therefore promising delivery systems to improve the oral bioavailability.

AB - Chitosan-tripolyphosphate and chitosan-alginate nanoparticles encapsulating (+)-catechin have been prepared and characterized. Using a novel method to evaluate the stability of the catechin within the nanoparticles, we found that the nanoparticles protect (+)- catechin from oxidative degradation in simulated intestinal fluids. In-vitro release studies demonstrated a pH dependent release of the catechin. These nanoparticles are therefore promising delivery systems to improve the oral bioavailability.

UR - http://www.proceedings.com/06401.html

M3 - Conference Paper

SN - 9781615675418

SP - on cd - on cd

BT - 36th Annual Meeting & Exposition of the Controlled Release Society

A2 - Evidence of peer review attached, null

PB - Controlled Release Society

CY - USA

T2 - Annual Meeting & Exposition of the Controlled Release Society 2009

Y2 - 1 January 2009

ER -

Preparation and evaluation of biopolymeric nanoparticles encapsulating green tea catechins

Abstract

Conference

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