Preparation and evaluation of biopolymeric nanoparticles encapsulating green tea catechins

Admire Dube, Ian Clair Larson

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Abstract

Chitosan-tripolyphosphate and chitosan-alginate nanoparticles encapsulating (+)-catechin have been prepared and characterized. Using a novel method to evaluate the stability of the catechin within the nanoparticles, we found that the nanoparticles protect (+)- catechin from oxidative degradation in simulated intestinal fluids. In-vitro release studies demonstrated a pH dependent release of the catechin. These nanoparticles are therefore promising delivery systems to improve the oral bioavailability.
Original languageEnglish
Title of host publication36th Annual Meeting & Exposition of the Controlled Release Society
Editors Evidence of peer review attached
Place of PublicationUSA
PublisherControlled Release Society
Pageson cd - on cd
Number of pages2
ISBN (Print)9781615675418
Publication statusPublished - 2009
EventAnnual Meeting & Exposition of the Controlled Release Society 2009 - Bella Center Coppenhagen Denmark, USA
Duration: 1 Jan 2009 → …

Conference

ConferenceAnnual Meeting & Exposition of the Controlled Release Society 2009
CityUSA
Period1/01/09 → …

Cite this

Dube, A., & Larson, I. C. (2009). Preparation and evaluation of biopolymeric nanoparticles encapsulating green tea catechins. In Evidence of peer review attached (Ed.), 36th Annual Meeting & Exposition of the Controlled Release Society (pp. on cd - on cd). USA: Controlled Release Society.