Chitosan-tripolyphosphate and chitosan-alginate nanoparticles encapsulating (+)-catechin have been prepared and characterized. Using a novel method to evaluate the stability of the catechin within the nanoparticles, we found that the nanoparticles protect (+)- catechin from oxidative degradation in simulated intestinal fluids. In-vitro release studies demonstrated a pH dependent release of the catechin. These nanoparticles are therefore promising delivery systems to improve the oral bioavailability.
|Title of host publication||36th Annual Meeting & Exposition of the Controlled Release Society|
|Editors||Evidence of peer review attached|
|Place of Publication||USA|
|Publisher||Controlled Release Society|
|Pages||on cd - on cd|
|Number of pages||2|
|Publication status||Published - 2009|
|Event||Annual Meeting & Exposition of the Controlled Release Society 2009 - Bella Center Coppenhagen Denmark, USA|
Duration: 1 Jan 2009 → …
|Conference||Annual Meeting & Exposition of the Controlled Release Society 2009|
|Period||1/01/09 → …|
Dube, A., & Larson, I. C. (2009). Preparation and evaluation of biopolymeric nanoparticles encapsulating green tea catechins. In Evidence of peer review attached (Ed.), 36th Annual Meeting & Exposition of the Controlled Release Society (pp. on cd - on cd). USA: Controlled Release Society.