Preliminary X-ray crystallographic studies of a newly defined human theta-class glutathione transferase

William J. Mckinstry, Aaron J. Oakley, Jamie Rossjohn, Denis Verger, Kian Leong Tan, Philip G. Board, Michael W. Parker

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4 Citations (Scopus)

Abstract

Human theta-class glutathione S-transferases (GST's) appear to play a critical role in the metabolism of a variety of environmental pollutants but in some cases the products of the reaction are carcinogenic. Crystals of a human theta-class GST, namely hGSTT2-2, have been grown from polyethylene glycol by the hanging-drop vapour-diffusion method. The crystals belong to the trigonal space group P3121 with cell dimensions of a= b = 94.0 and c = 120.5 Å. They contain two monomers in the asymmetric unit and diffract to 3.0 Å resolution.

Original languageEnglish
Pages (from-to)148-150
Number of pages3
JournalActa Crystallographica Section D: Biological Crystallography
Volume54
Issue number1
DOIs
Publication statusPublished - 1 Jan 1998
Externally publishedYes

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