Prefabrication of thin transferable axial-pattern skin flaps: an experimental study in rabbits

Wayne Allan Morrison, E. Dvir, K. Doi, J. V. Hurley, M. J. Hickey, B. McC O'Brien

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92 Citations (Scopus)

Abstract

The arteriovenous pedicle of all known axial-pattern skin flaps enters from the deep aspect and consequently the flap must contain fat and/or muscle and be of considerable thickness. In an attempt to fabricate a thinner axial-pattern flap the femoral artery and vein of rabbits were implanted, in various vascular configurations, directly into the subdermal layer of the skin. Implantation was found to provoke an extensive outgrowth of new vessels from the implanted artery and vein, and the progress and pattern of this neovascularisation was studied by carbon gelatine perfusion and histology. Neovascularisation begins within a few days of implantation and progresses rapidly. By 8 to 12 weeks it is possible to elevate regularly a viable, large skin flap based on the implanted pedicle.

Original languageEnglish
Pages (from-to)645-654
Number of pages10
JournalBritish Journal of Plastic Surgery
Volume43
Issue number6
DOIs
Publication statusPublished - 1990
Externally publishedYes

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