Predictors of outcome in pediatric osteomyelitis: Five years experience in a single tertiary center

Andrew C Martin, Denise Anderson, Julie Lucey, Robin Guttinger, Peter A Jacoby, Tabitha J. Mok, Timothy J. Whitmore, Colin N. Whitewood, David P. Burgner, Christopher Blyth

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Background: Acute haematogenous osteomyelitis is a bacterial infection of bone, which occurs most frequently in children. Outcomes are excellent for the majority of children, but a minority develop complicated osteomyelitis. Predicting which children will develop complicated osteomyelitis remains a challenge, particularly in developed countries where most patients are discharged home after a relatively short period in hospital. Methods: We conducted a 5-year retrospective case note review of all children aged 3 months to 16 years admitted with a diagnosis of acute haematogenous osteomyelitis. We compared standardized clinical and laboratory parameters in those who developed simple and complicated osteomyelitis. Results: Of the 299 children who met inclusion, 241 (80.6%) had simple and 58 (19.4%) had complicated osteomyelitis. The major predictors of complicated disease were older age, a temperature greater than 38.5°C and a higher C-reactive protein at admission. Conclusions: A risk prediction model, utilizing information available shortly after hospitalization, allows early identification of children at greatest risk of developing complicated osteomyelitis.

Original languageEnglish
Pages (from-to)387-391
Number of pages5
JournalPediatric Infectious Disease Journal
Volume35
Issue number4
DOIs
Publication statusPublished - Apr 2016

Keywords

  • Children
  • Osteomyelitis
  • Outcome

Cite this

Martin, A. C., Anderson, D., Lucey, J., Guttinger, R., Jacoby, P. A., Mok, T. J., ... Blyth, C. (2016). Predictors of outcome in pediatric osteomyelitis: Five years experience in a single tertiary center. Pediatric Infectious Disease Journal, 35(4), 387-391. https://doi.org/10.1097/INF.0000000000001031
Martin, Andrew C ; Anderson, Denise ; Lucey, Julie ; Guttinger, Robin ; Jacoby, Peter A ; Mok, Tabitha J. ; Whitmore, Timothy J. ; Whitewood, Colin N. ; Burgner, David P. ; Blyth, Christopher. / Predictors of outcome in pediatric osteomyelitis : Five years experience in a single tertiary center. In: Pediatric Infectious Disease Journal. 2016 ; Vol. 35, No. 4. pp. 387-391.
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abstract = "Background: Acute haematogenous osteomyelitis is a bacterial infection of bone, which occurs most frequently in children. Outcomes are excellent for the majority of children, but a minority develop complicated osteomyelitis. Predicting which children will develop complicated osteomyelitis remains a challenge, particularly in developed countries where most patients are discharged home after a relatively short period in hospital. Methods: We conducted a 5-year retrospective case note review of all children aged 3 months to 16 years admitted with a diagnosis of acute haematogenous osteomyelitis. We compared standardized clinical and laboratory parameters in those who developed simple and complicated osteomyelitis. Results: Of the 299 children who met inclusion, 241 (80.6{\%}) had simple and 58 (19.4{\%}) had complicated osteomyelitis. The major predictors of complicated disease were older age, a temperature greater than 38.5°C and a higher C-reactive protein at admission. Conclusions: A risk prediction model, utilizing information available shortly after hospitalization, allows early identification of children at greatest risk of developing complicated osteomyelitis.",
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Martin, AC, Anderson, D, Lucey, J, Guttinger, R, Jacoby, PA, Mok, TJ, Whitmore, TJ, Whitewood, CN, Burgner, DP & Blyth, C 2016, 'Predictors of outcome in pediatric osteomyelitis: Five years experience in a single tertiary center' Pediatric Infectious Disease Journal, vol. 35, no. 4, pp. 387-391. https://doi.org/10.1097/INF.0000000000001031

Predictors of outcome in pediatric osteomyelitis : Five years experience in a single tertiary center. / Martin, Andrew C; Anderson, Denise; Lucey, Julie; Guttinger, Robin; Jacoby, Peter A; Mok, Tabitha J.; Whitmore, Timothy J.; Whitewood, Colin N.; Burgner, David P.; Blyth, Christopher.

In: Pediatric Infectious Disease Journal, Vol. 35, No. 4, 04.2016, p. 387-391.

Research output: Contribution to journalArticleResearchpeer-review

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T2 - Five years experience in a single tertiary center

AU - Martin, Andrew C

AU - Anderson, Denise

AU - Lucey, Julie

AU - Guttinger, Robin

AU - Jacoby, Peter A

AU - Mok, Tabitha J.

AU - Whitmore, Timothy J.

AU - Whitewood, Colin N.

AU - Burgner, David P.

AU - Blyth, Christopher

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