Prediction of torsade de pointes from the QT interval: Analysis of a case series of amisulpride overdoses

J. P. Joy, Carolyn V. Coulter, Stephen B Duffull, G. K. Isbister

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24 Citations (Scopus)

Abstract

Electrocardiograms (ECGs) from a case series of 86 amisulpride overdose events in 66 patients were reviewed for abnormal QT intervals and torsade de pointes (TdP). Eight patients exhibited TdP. In this investigative case series, the magnitude of prolongation of the QT interval was a stronger predictor of TdP than the mere presence of a prolongation per se.

Original languageEnglish
Pages (from-to)243-245
Number of pages3
JournalClinical Pharmacology & Therapeutics
Volume90
Issue number2
DOIs
Publication statusPublished - Aug 2011
Externally publishedYes

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