Abstract
Malaria vaccines aim to induce long lasting protective immunity. Bejon and colleagues propose that levels of rapidly induced (effector memory) interleukin-2 and interferon gamma producing T-cells after vaccination with leading pre-erythrocytic stage vaccines predict the induction of resting memory responses (central memory). Herein we discuss Bejon s findings in the context of current thinking on the generation and maintenance of T cell memory, with particular emphasis on the role of cytokines.
| Original language | English |
|---|---|
| Pages (from-to) | 341 - 343 |
| Number of pages | 3 |
| Journal | Trends in Parasitology |
| Volume | 23 |
| Issue number | 8 |
| Publication status | Published - 2007 |