Predicting memory: a prospective readout for malaria vaccines?

Gabriela Minigo, Karen Scalzo, Katie L Flanagan, Magdalena Plebanski

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Abstract

Malaria vaccines aim to induce long lasting protective immunity. Bejon and colleagues propose that levels of rapidly induced (effector memory) interleukin-2 and interferon gamma producing T-cells after vaccination with leading pre-erythrocytic stage vaccines predict the induction of resting memory responses (central memory). Herein we discuss Bejon s findings in the context of current thinking on the generation and maintenance of T cell memory, with particular emphasis on the role of cytokines.
Original languageEnglish
Pages (from-to)341 - 343
Number of pages3
JournalTrends in Parasitology
Volume23
Issue number8
Publication statusPublished - 2007

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