Malaria vaccines aim to induce long lasting protective immunity. Bejon and colleagues propose that levels of rapidly induced (effector memory) interleukin-2 and interferon gamma producing T-cells after vaccination with leading pre-erythrocytic stage vaccines predict the induction of resting memory responses (central memory). Herein we discuss Bejon s findings in the context of current thinking on the generation and maintenance of T cell memory, with particular emphasis on the role of cytokines.
|Pages (from-to)||341 - 343|
|Number of pages||3|
|Journal||Trends in Parasitology|
|Publication status||Published - 2007|