Practical insights into gluten-free diets

Jacalyn A. See, Katri Kaukinen, Govind K Makharia, Peter R. Gibson, Joseph A Murray

Research output: Contribution to journalReview ArticleOtherpeer-review

50 Citations (Scopus)

Abstract

Coeliac disease is a global disease, and the only currently available treatment is a gluten-free diet (GFD). Although conceptually simple, the diet changes are substantial and have a profound effect on a patient's life. Untreated coeliac disease is associated with complications, including excess mortality, most of which can be avoided with a strict GFD. However, there are many barriers, including availability, cost and safety of gluten-free foods, and gluten cross-contamination. The GFD can be restrictive in social situations, leading to poor quality of life and, ultimately, nonadherence. As the number of patients with coeliac disease increases worldwide, clinicians need to be aware of the challenges patients face. Heightened awareness by physicians, dietitians and other providers can help maximize successful treatment, improve outcomes, and reduce health-care costs and disease burden. Routine follow-up is necessary to reinforce the need for a GFD, provide social and emotional support, and achieve mucosal healing, leading to reduced risk of complications. Unfortunately, there is wide variation in follow-up practices. The objective of this Review is to increase awareness of the challenges, management and follow-up of patients with coeliac disease to help them achieve GFD adherence and prevent complications whilst preserving their quality of life.

Original languageEnglish
Pages (from-to)580-591
Number of pages12
JournalNature Reviews Gastroenterology & Hepatology
Volume12
Issue number10
DOIs
Publication statusPublished - 1 Oct 2015

Cite this

See, Jacalyn A. ; Kaukinen, Katri ; Makharia, Govind K ; Gibson, Peter R. ; Murray, Joseph A. / Practical insights into gluten-free diets. In: Nature Reviews Gastroenterology & Hepatology. 2015 ; Vol. 12, No. 10. pp. 580-591.
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Practical insights into gluten-free diets. / See, Jacalyn A.; Kaukinen, Katri; Makharia, Govind K; Gibson, Peter R.; Murray, Joseph A.

In: Nature Reviews Gastroenterology & Hepatology, Vol. 12, No. 10, 01.10.2015, p. 580-591.

Research output: Contribution to journalReview ArticleOtherpeer-review

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