Practical and methodological challenges when conducting a cluster randomized trial: Examples and recommendations

Agnès Caille, Laurent Billot, Jessica Kasza

Research output: Contribution to journalReview ArticleOtherpeer-review

4 Citations (Scopus)

Abstract

The use of cluster randomized trial design to answer research questions is increasing. This design and associated variants such as the cluster randomized crossover and stepped wedge are useful to assess complex interventions in a pragmatic way but when adopting such designs, one may face specific implementation challenges. This article summarizes common challenges faced when conducting cluster randomized trials, cluster randomized crossover trials, and stepped wedge trials, and provides recommendations.

Original languageEnglish
Article number202199
Number of pages7
JournalJournal of Epidemiology and Population Health
Volume72
Issue number1
DOIs
Publication statusPublished - Feb 2024

Keywords

  • Challenges
  • Cluster randomized trial
  • Cross-over
  • Design
  • Implementation
  • Methodological recommendations
  • Stepped-wedge

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