TY - JOUR
T1 - Practical and methodological challenges when conducting a cluster randomized trial
T2 - Examples and recommendations
AU - Caille, Agnès
AU - Billot, Laurent
AU - Kasza, Jessica
N1 - Publisher Copyright:
© 2024 The Author(s)
PY - 2024/2
Y1 - 2024/2
N2 - The use of cluster randomized trial design to answer research questions is increasing. This design and associated variants such as the cluster randomized crossover and stepped wedge are useful to assess complex interventions in a pragmatic way but when adopting such designs, one may face specific implementation challenges. This article summarizes common challenges faced when conducting cluster randomized trials, cluster randomized crossover trials, and stepped wedge trials, and provides recommendations.
AB - The use of cluster randomized trial design to answer research questions is increasing. This design and associated variants such as the cluster randomized crossover and stepped wedge are useful to assess complex interventions in a pragmatic way but when adopting such designs, one may face specific implementation challenges. This article summarizes common challenges faced when conducting cluster randomized trials, cluster randomized crossover trials, and stepped wedge trials, and provides recommendations.
KW - Challenges
KW - Cluster randomized trial
KW - Cross-over
KW - Design
KW - Implementation
KW - Methodological recommendations
KW - Stepped-wedge
UR - http://www.scopus.com/inward/record.url?scp=85196259380&partnerID=8YFLogxK
U2 - 10.1016/j.jeph.2024.202199
DO - 10.1016/j.jeph.2024.202199
M3 - Review Article
C2 - 38477480
AN - SCOPUS:85196259380
SN - 2950-4333
VL - 72
JO - Journal of Epidemiology and Population Health
JF - Journal of Epidemiology and Population Health
IS - 1
M1 - 202199
ER -