TY - JOUR
T1 - Potential through simplicity
T2 - thymidine kinase-1 as a biomarker for CDK4/6 inhibitors
AU - McCartney, Amelia
AU - Malorni, Luca
N1 - Funding Information:
Funding information This work was partially supported by a grant from the Breast Cancer Research Foundation (grant number BCRF 19-037) and by a grant from Fondazione AIRC (IG 22869).
Publisher Copyright:
© 2020, Cancer Research UK.
PY - 2020/7/21
Y1 - 2020/7/21
N2 - We describe a potential role for thymidine kinase-1, a general marker of cellular proliferation, to act as a prognostic biomarker in patients receiving CDK4/6 inhibitors for advanced hormone receptor-positive, HER2-negative breast cancer, with early data suggesting that it may also provide early indication of treatment response.
AB - We describe a potential role for thymidine kinase-1, a general marker of cellular proliferation, to act as a prognostic biomarker in patients receiving CDK4/6 inhibitors for advanced hormone receptor-positive, HER2-negative breast cancer, with early data suggesting that it may also provide early indication of treatment response.
UR - http://www.scopus.com/inward/record.url?scp=85085096592&partnerID=8YFLogxK
U2 - 10.1038/s41416-020-0858-y
DO - 10.1038/s41416-020-0858-y
M3 - Comment / Debate
C2 - 32382111
AN - SCOPUS:85085096592
SN - 0007-0920
VL - 123
SP - 176
EP - 177
JO - British Journal of Cancer
JF - British Journal of Cancer
IS - 2
ER -
