Posttreatment Evaluation of Central Nervous System Gliomas

Mark S. Shiroishi, Michael T. Booker, Manyoo Agarwal, Nidhi Jain, Ilana Naghi, Alexander Lerner, Meng Law

Research output: Contribution to journalReview ArticleResearchpeer-review

9 Citations (Scopus)


Although conventional contrast-enhanced MR imaging remains the standard-of-care imaging method in the posttreatment evaluation of gliomas, recent developments in therapeutic options such as chemoradiation and antiangiogenic agents have caused the neuro-oncology community to rethink traditional imaging criteria. This article highlights the latest recommendations. These recommendations should be viewed as works in progress. As more is learned about the pathophysiology of glioma treatment response, quantitative imaging biomarkers will be validated within this context. There will likely be further refinements to glioma response criteria, although the lack of technical standardization in image acquisition, postprocessing, and interpretation also need to be addressed.

Original languageEnglish
Pages (from-to)241-268
Number of pages28
JournalMagnetic Resonance Imaging Clinics of North America
Issue number2
Publication statusPublished - 1 May 2013
Externally publishedYes


  • Glioblastoma
  • Glioma
  • Imaging biomarkers
  • MacDonald criteria
  • MR imaging
  • Pseudoresponse
  • Radiation necrosis
  • Response assessment

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