TY - JOUR
T1 - Postoperative nausea and vomiting. Propofol or thiopentone
T2 - Does choice of induction agent affect outcome?
AU - Myles, P. S.
AU - Hendrata, M.
AU - Bennett, A. M.
AU - Langley, M.
AU - Buckland, M. R.
PY - 1996/6
Y1 - 1996/6
N2 - Postoperative nausea and vomiting (PONV) has many causes, including anaesthetic drugs. Choice of induction agent may affect the incidence of PONV, though the evidence is conflicting. We have analysed our database of outcome after surgery. Data on 4173 patients were analysed using multivariate logistic regression, with an overall incidence of PONV 21.3%. Propofol, when compared to thiopentone for induction of anaesthesia, resulted in an 18% reduction in PONV (OR = 0.82, P = 0.03). The likely postoperative benefits of propofol may outweigh concerns about its additional cost.
AB - Postoperative nausea and vomiting (PONV) has many causes, including anaesthetic drugs. Choice of induction agent may affect the incidence of PONV, though the evidence is conflicting. We have analysed our database of outcome after surgery. Data on 4173 patients were analysed using multivariate logistic regression, with an overall incidence of PONV 21.3%. Propofol, when compared to thiopentone for induction of anaesthesia, resulted in an 18% reduction in PONV (OR = 0.82, P = 0.03). The likely postoperative benefits of propofol may outweigh concerns about its additional cost.
KW - Anaesthetics, intravenous: propofol
KW - Complications: postoperative nausea, vomiting
UR - http://www.scopus.com/inward/record.url?scp=0029895018&partnerID=8YFLogxK
M3 - Article
C2 - 8805891
AN - SCOPUS:0029895018
SN - 0310-057X
VL - 24
SP - 355
EP - 359
JO - Anaesthesia and Intensive Care
JF - Anaesthesia and Intensive Care
IS - 3
ER -