Projects per year
Abstract
Several studies have shown that postoperative atrial fibrillation (POAF) is associated with poorer short-term and long-term outcomes after general cardiac
operations. There is, however, a paucity of data on the impact of POAF on outcomes after isolated aortic valve
replacement (AVR).
Methods. Data for all patients undergoing isolated
first-time AVR between June 2001 and December 2009
was obtained from the Australasian Society of Cardiac
and Thoracic Surgeons (ASCTS) National Cardiac Surgery
Database Program and a retrospective analysis was
conducted. Preoperative characteristics, early postoperative
outcome, and late survival were compared between
patients in whom POAF developed and those in whom it
did not. Propensity score matching was performed to
correct for differences between the 2 groups.
Results. Excluding patients with preoperative arrhythmia,
isolated first-time AVR was performed in 2,065
patients. POAF developed in 725 (35.1 ) of them. Patients
with POAF were significantly older (mean age, 72
versus 65 years; p <0.001) and presented more often with
comorbidities, including hypertension, respiratory disease,
and hypercholesterolemia (all p <0.05). From the
initial study population, 592 propensity-matched patient
pairs were derived; the overall matching rate was 81.7 .
In the matched groups, 30-day mortality was not significantly
different between the POAF and non-POAF
groups (1.5 versus 1 ; p 0.48). Patients with POAF
were, however, at an independently increased risk of
perioperative complications, including new renal failure,
gastrointestinal complications, and 30-day readmission
(p <0.05). Seven-year mortality was not significantly
different between POAF and non-POAF groups (78
versus 83 ; p 0.63).
Conclusions. POAF is a risk factor for short-term morbidity
but is not associated with a higher rate of early or
late mortality after isolated AVR.
Original language | English |
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Pages (from-to) | 133 - 140 |
Number of pages | 8 |
Journal | The Annals of Thoracic Surgery |
Volume | 95 |
Issue number | 1 |
DOIs | |
Publication status | Published - 2013 |
Projects
- 1 Curtailed
-
NHMRC Research Fellowship
Reid, C.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/08 → 3/05/16
Project: Research