Post-traumatic epilepsy: a retrospective study from a tertiary trauma center in Malaysia

Irma Wati Ngadimon, Ching Soong Khoo, Mohd. Farooq Shaikh, Devi Mohan, Mark Wing Loong Cheong, Ángel Aledo-Serrano

Research output: Contribution to journalMeeting Abstractpeer-review


Introduction: Post-traumatic epilepsy (PTE) is a devastating neuro-logical complication of traumatic brain injury (TBI) which reduces patients’ quality of life and imposes severe socioeconomic costs. However, little information on PTE incidence and the predictors in Malaysian subjects.

Objective: This study aims to determine PTE incidence after a and identify the predictors in a tertiary trauma center in Malaysia.

Method: A TBI database was formed based on the patient’s registry in University Kebangsaan Malaysia Medical Centre from 2019 to2020. Related demographic data and clinical information were then retrieved from medical records. Patients were contacted to ascertain their epilepsy, and the diagnosis was further confirmed through clinical observation by neurologists.

Results: Our preliminary analysis included 171 subjects, 130(76%)males and 41 (24%) females, with a mean age of 49 years (SD: 20.6,median 49.5). Causes of TBI were motor vehicle accidents related in 100cases (58.5%), falls in 63 (36.8%), assault in 6 (3.5%), and sports in 2(1.2%). The cumulative incidence of PTE was 8.19% at two years. The average days taken for the onset of PTE was 106 days. PTE predictors were age above 60, male, poor GCS (
Conclusion: This was the first study in Malaysia to examine PTE incidence and its predictors. PTE risk varied by patient gender, age, GCS score, and complexity of the injury. Post-traumatic brain injury patients needed integrated care for early detection and treatment of epilepsy.
Original languageEnglish
Pages (from-to)A128
Number of pages1
JournalJournal of Neurotrauma
Issue number11-12
Publication statusPublished - Jun 2022
EventAnnual National-Neurotrauma-Society Symposium 2022 - Atlanta, United States of America
Duration: 26 Jun 202229 Jun 2022
Conference number: 39th


  • Epilepsy
  • Seizure

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