Post-transfusion purpura

M. Abramson, S. Pfueller, W. Sheridan

Research output: Contribution to journalArticleResearchpeer-review

Abstract

We report two cases of purpura characterisd by severe immune thrombocytopenia which appeared one to two weeks after blood transfusion during elective surgery. Both patients had antibodies to the platelet P1(A1) antigen and displayed high levels of platelet-bindable igG and IgM in their serum; they were treated with glucocorticoids and recovered after four weeks. One case relapsed following a further transfusion of packed red cells. Theories of pathogenesis, methods of diagnosis, and alternative forms of therapy are reviewed.

Original languageEnglish
Pages (from-to)763-766
Number of pages4
JournalAustralian and New Zealand Journal of Medicine
Volume15
Issue number6
Publication statusPublished - 1 Dec 1985

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