Positron emission tomography: Radioisotope and radiopharmaceutical production

H. J. Tochon-Danguy, J. I. Sachinidis, G. F. Egan, J. G. Chan, S. U. Berlangieri, W. J. McKay, A. M. Scott

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

Abstract

A Centre for Positron Emission Tomography (PET) has been operational within the Department of Nuclear Medicine at the Austin & Repatriation Medical Centre (A&RMC) in Melbourne for seven years. PET is a non-invasive imaging technique based on the use of biologically relevant compounds labelled with short-lived positron-emitting radionuclides such as carbon-11, nitrogen-13, oxygen-15 and fluorine-18. The basic facility consists of a medical cyclotron (10 MeV proton & 5 MeV deuteron), six lead-shielded hotcells with associated radiochemistry facilities, radiopharmacy and a whole body PET scanner. A strong radiolabelling development program, including the production of 15O-oxygen, 15O-carbon monoxide, 15Q-carbon dioxide, 15Q-water, 13N-ammonia, 18F-FDG, 18F-FMISO, 11C-SCH23390 and 11C-flumazenil has been pursued to support an ambitious clinical and research program in neurology, oncology, cardiology and psychiatry.

Original languageEnglish
Pages (from-to)136-144
Number of pages9
JournalAustralasian Physical and Engineering Sciences in Medicine
Volume22
Issue number4
Publication statusPublished - 1 Dec 1999
Externally publishedYes

Keywords

  • PET
  • Positron Emission Tomography
  • Radioisotope/ Radiopharmaceutical production

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