Positive allosteric mechanisms of adenosine A₁ receptor-mediated analgesia

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  ARC Industrial Transformation Training Centre for Cryo-Electron Microscopy of Membrane Proteins for Drug Discovery

  Sexton, P. (Primary Chief Investigator (PCI)), Rouiller, I. (Chief Investigator (CI)), Wootten, D. (Chief Investigator (CI)), van Oijen, A. (Chief Investigator (CI)), Parker, M. W. (Chief Investigator (CI)), Lucet, I. (Partner Investigator (PI)), Griffin, M. D. W. (Chief Investigator (CI)), Adams, D. J. (Chief Investigator (CI)), Czabotar, P. E. (Partner Investigator (PI)), Flocco, M. (Partner Investigator (PI)), Han, S. (Partner Investigator (PI)), Shepherd, R. (Partner Investigator (PI)), Ciferri, C. (Partner Investigator (PI)), Williams, P. A. (Partner Investigator (PI)), Brown, D. (Partner Investigator (PI)), Schreuder, H. (Partner Investigator (PI)), Reedtz-Runge, S. (Partner Investigator (PI)), Drinkwater, C. (Partner Investigator (PI)), Howard, B. L. (Partner Investigator (PI)), Betigeri, G. (Partner Investigator (PI)), Pryor, E. (Partner Investigator (PI)), How, J. (Project Manager) & Christopoulos, T. (Chief Investigator (CI))

  Boehringer Ingelheim (Germany), AstraZeneca (United Kingdom)

  23/03/21 → 23/03/27

  Project: Research

• Finished

  Adenosine Receptor Context-Specific Biased Agonism to Treat Ischaemic Heart Disease

  May, L. (Primary Chief Investigator (PCI)), White, P. (Chief Investigator (CI)) & Kompa, A. (Chief Investigator (CI))

  1/01/18 → 31/12/20

  Project: Research

• Adenosine A1 receptor modulation: Structure, dynamics & novel pharmacological interventions

  Christopoulos, A. (Primary Chief Investigator (PCI)), May, L. (Chief Investigator (CI)), Imlach, W. (Chief Investigator (CI)), Hill, S. (Chief Investigator (CI)) & Scott, D. (Chief Investigator (CI))

  1/01/18 → 31/12/22

  Project: Research