Porous Silicon Nanostructures as Effective Faradaic Electrochemical Sensing Platforms

Keying Guo, Apoorva Sharma, Rou Jun Toh, Eva Alvárez de Eulate, Thomas R. Gengenbach, Xavier Cetó, Nicolas H. Voelcker, Beatriz Prieto-Simón

Research output: Contribution to journalArticleResearchpeer-review

Abstract

The electrochemical performance of porous silicon (pSi) stabilized via thermal decomposition of acetylene gas is investigated for the first time. In this study, pSi undergoes two thermal treatments at either 525 or 800 °C, which result in hydrogen-terminated thermally hydrocarbonized pSi (THCpSi) and hydroxyl-terminated thermally carbonized pSi (TCpSi), respectively, the latter upon dipping in hydrofluoric acid to activate the surface termination. Electrochemical characterization, using cyclic voltammetry, chronocoulometry, and electrochemical impedance spectroscopy in the presence of several redox pairs, [Fe(CN)6]3/4−, [Ru(NH3)6]2/3+, and hydroquinone/quinone, is used to demonstrate the versatility and high stability to degradation of carbon-stabilized pSi nanostructures and their excellent electrochemical performance. Added to the large surface area, adjustable pore morphology and tailorable surface chemistry of THCpSi and TCpSi, these nanostructures demonstrate fast electron-transfer kinetics, providing key advantages over conventional carbon electrodes. The versatile surface chemistry of THCpSi and TCpSi offer various possibilities to introduce multiple functional groups depending on the nature of the bioreceptor to be immobilized. For proof of principle, the use of a THCpSi-based immunosensor to detect MS2 bacteriophage is demonstrated by means of electrochemical impedance spectroscopy, showing a detection limit of 4.9 pfu mL−1. Carbon-stabilized pSi structures represent a new class of nanostructured electrodes for biosensing applications.

Original languageEnglish
Article number1809206
Number of pages12
JournalAdvanced Functional Materials
Volume29
Issue number24
DOIs
Publication statusPublished - 13 Jun 2019

Keywords

  • biosensing
  • carbon stabilization
  • electrochemistry
  • porous silicon

Cite this

Guo, K., Sharma, A., Toh, R. J., Alvárez de Eulate, E., Gengenbach, T. R., Cetó, X., ... Prieto-Simón, B. (2019). Porous Silicon Nanostructures as Effective Faradaic Electrochemical Sensing Platforms. Advanced Functional Materials, 29(24), [1809206]. https://doi.org/10.1002/adfm.201809206
Guo, Keying ; Sharma, Apoorva ; Toh, Rou Jun ; Alvárez de Eulate, Eva ; Gengenbach, Thomas R. ; Cetó, Xavier ; Voelcker, Nicolas H. ; Prieto-Simón, Beatriz. / Porous Silicon Nanostructures as Effective Faradaic Electrochemical Sensing Platforms. In: Advanced Functional Materials. 2019 ; Vol. 29, No. 24.
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Porous Silicon Nanostructures as Effective Faradaic Electrochemical Sensing Platforms. / Guo, Keying; Sharma, Apoorva; Toh, Rou Jun; Alvárez de Eulate, Eva; Gengenbach, Thomas R.; Cetó, Xavier; Voelcker, Nicolas H.; Prieto-Simón, Beatriz.

In: Advanced Functional Materials, Vol. 29, No. 24, 1809206, 13.06.2019.

Research output: Contribution to journalArticleResearchpeer-review

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T1 - Porous Silicon Nanostructures as Effective Faradaic Electrochemical Sensing Platforms

AU - Guo, Keying

AU - Sharma, Apoorva

AU - Toh, Rou Jun

AU - Alvárez de Eulate, Eva

AU - Gengenbach, Thomas R.

AU - Cetó, Xavier

AU - Voelcker, Nicolas H.

AU - Prieto-Simón, Beatriz

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N2 - The electrochemical performance of porous silicon (pSi) stabilized via thermal decomposition of acetylene gas is investigated for the first time. In this study, pSi undergoes two thermal treatments at either 525 or 800 °C, which result in hydrogen-terminated thermally hydrocarbonized pSi (THCpSi) and hydroxyl-terminated thermally carbonized pSi (TCpSi), respectively, the latter upon dipping in hydrofluoric acid to activate the surface termination. Electrochemical characterization, using cyclic voltammetry, chronocoulometry, and electrochemical impedance spectroscopy in the presence of several redox pairs, [Fe(CN)6]3/4−, [Ru(NH3)6]2/3+, and hydroquinone/quinone, is used to demonstrate the versatility and high stability to degradation of carbon-stabilized pSi nanostructures and their excellent electrochemical performance. Added to the large surface area, adjustable pore morphology and tailorable surface chemistry of THCpSi and TCpSi, these nanostructures demonstrate fast electron-transfer kinetics, providing key advantages over conventional carbon electrodes. The versatile surface chemistry of THCpSi and TCpSi offer various possibilities to introduce multiple functional groups depending on the nature of the bioreceptor to be immobilized. For proof of principle, the use of a THCpSi-based immunosensor to detect MS2 bacteriophage is demonstrated by means of electrochemical impedance spectroscopy, showing a detection limit of 4.9 pfu mL−1. Carbon-stabilized pSi structures represent a new class of nanostructured electrodes for biosensing applications.

AB - The electrochemical performance of porous silicon (pSi) stabilized via thermal decomposition of acetylene gas is investigated for the first time. In this study, pSi undergoes two thermal treatments at either 525 or 800 °C, which result in hydrogen-terminated thermally hydrocarbonized pSi (THCpSi) and hydroxyl-terminated thermally carbonized pSi (TCpSi), respectively, the latter upon dipping in hydrofluoric acid to activate the surface termination. Electrochemical characterization, using cyclic voltammetry, chronocoulometry, and electrochemical impedance spectroscopy in the presence of several redox pairs, [Fe(CN)6]3/4−, [Ru(NH3)6]2/3+, and hydroquinone/quinone, is used to demonstrate the versatility and high stability to degradation of carbon-stabilized pSi nanostructures and their excellent electrochemical performance. Added to the large surface area, adjustable pore morphology and tailorable surface chemistry of THCpSi and TCpSi, these nanostructures demonstrate fast electron-transfer kinetics, providing key advantages over conventional carbon electrodes. The versatile surface chemistry of THCpSi and TCpSi offer various possibilities to introduce multiple functional groups depending on the nature of the bioreceptor to be immobilized. For proof of principle, the use of a THCpSi-based immunosensor to detect MS2 bacteriophage is demonstrated by means of electrochemical impedance spectroscopy, showing a detection limit of 4.9 pfu mL−1. Carbon-stabilized pSi structures represent a new class of nanostructured electrodes for biosensing applications.

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KW - carbon stabilization

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JO - Advanced Functional Materials

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Guo K, Sharma A, Toh RJ, Alvárez de Eulate E, Gengenbach TR, Cetó X et al. Porous Silicon Nanostructures as Effective Faradaic Electrochemical Sensing Platforms. Advanced Functional Materials. 2019 Jun 13;29(24). 1809206. https://doi.org/10.1002/adfm.201809206