Pontine-to-midbrain ratio indexes ocular-motor function and illness stage in adult Niemann-Pick disease type C

Mark Walterfang, Matthew D Macfarlane, Jeffrey Chee Leong Looi, Larry Abel, Elizabeth Bowman, Michael Collingwood Fahey, P M Desmond, Dennis Velakoulis

Research output: Contribution to journalArticleResearchpeer-review

30 Citations (Scopus)

Abstract

Niemann-Pick disease type C (NPC) is a preogressive neurovisceral disorder associated with dystonia, ataxia and a characteristic gaze palsy. Our aim was to utilize a method for brainstem atrophy, validated in progressive supranuclear palsy (PSP), in a group of adult patients with NPC, and explore its relationship to illness variables and ocular-motor functioning.
Original languageEnglish
Pages (from-to)462 - 467
Number of pages6
JournalEuropean Journal of Neurology
Volume19
Issue number3
DOIs
Publication statusPublished - 2012

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