Polymerised bicontinuous microemulsions as stationary phases for capillary electrochromatography

N. R. Cameron, K. J. Flook, S. A C Wren

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Abstract

Polymerisation of bicontinuous microemulsions yields porous monolithic structures with well defined pore sizes that are potentially suitable for use as stationary phases for capillary electrochromatography (CEC). A variety of pore sizes can be achieved by altering the composition of the microemulsion, which typically consists of butyl methacrylate (BMA) and ethylene glycol dimethacrylate (EGDMA) as the polymerisable oil phase. The aqueous phase consists of water, a surfactant (sodium dodecyl sulphate, SDS) and a co-surfactant (1-propanol). 2-acrylamido-2-methyl-1-propane sulfonic acid (AMPS) is also added to provide charges along the polymer backbone to allow electroosmotic flow (EOF) to occur. SEM analysis shows that in-situ polymerisation yields a monolithic structure with a porous topography. Investigations have shown that these monoliths are easy to prepare, robust and suitable for the separation of phthalates. They generate higher linear velocities than are achieved using the silica based HPLC packings normally used for CEC.

Original languageEnglish
Pages (from-to)203-206
Number of pages4
JournalChromatographia
Volume57
Issue number3-4
DOIs
Publication statusPublished - 1 Feb 2003
Externally publishedYes

Keywords

  • Capillary electrochromatography
  • Microemulsion
  • Monolithic columns
  • Phthalates
  • Stationary phases

Cite this