Polymer-gold nanohybrids with potential use in bimodal MRI/CT: enhancing the relaxometric properties of Gd(III) complexes

Mariana Beija; Yang Li; Hien T Duong; Sophie Laurent; Luce Vander Elst; Robert N Muller; Andrew B. Lowe; Thomas P Davis; Cyrille Boyer

doi:10.1039/c2jm34999j

Polymer-gold nanohybrids with potential use in bimodal MRI/CT: enhancing the relaxometric properties of Gd(III) complexes

Mariana Beija, Yang Li, Hien T Duong, Sophie Laurent, Luce Vander Elst, Robert N Muller, Andrew B. Lowe, Thomas P Davis, Cyrille Boyer

Research output: Contribution to journal › Article › Research › peer-review

37 Citations (Scopus)

Abstract

We present a new synthetic strategy to produce Gd(iii)-decorated gold nanoparticles (AuNPs) for potential use as bimodal contrast agents (CA) for computed X-ray tomography (CT) and magnetic resonance imaging (MRI). The hybrid AuNPs exhibit high molar relaxivities (>12000 mM ^-1 s ^-1 per particle), indicative of highly efficient CT/MRI CAs.

Original language	English
Pages (from-to)	21382-21386
Number of pages	5
Journal	Journal of Materials Chemistry
Volume	22
Issue number	40
DOIs	https://doi.org/10.1039/c2jm34999j
Publication status	Published - 28 Oct 2012
Externally published	Yes

Access to Document

10.1039/c2jm34999j

Cite this

@article{d1fa3b99161048e4aa02486bd0d3ee9b,

title = "Polymer-gold nanohybrids with potential use in bimodal MRI/CT: enhancing the relaxometric properties of Gd(III) complexes",

abstract = "We present a new synthetic strategy to produce Gd(iii)-decorated gold nanoparticles (AuNPs) for potential use as bimodal contrast agents (CA) for computed X-ray tomography (CT) and magnetic resonance imaging (MRI). The hybrid AuNPs exhibit high molar relaxivities (>12000 mM -1 s -1 per particle), indicative of highly efficient CT/MRI CAs. ",

author = "Mariana Beija and Yang Li and Duong, {Hien T} and Sophie Laurent and Elst, {Luce Vander} and Muller, {Robert N} and Lowe, {Andrew B.} and Davis, {Thomas P} and Cyrille Boyer",

year = "2012",

month = oct,

day = "28",

doi = "10.1039/c2jm34999j",

language = "English",

volume = "22",

pages = "21382--21386",

journal = "Journal of Materials Chemistry",

issn = "0959-9428",

publisher = "The Royal Society of Chemistry",

number = "40",

}

TY - JOUR

T1 - Polymer-gold nanohybrids with potential use in bimodal MRI/CT

T2 - enhancing the relaxometric properties of Gd(III) complexes

AU - Beija, Mariana

AU - Li, Yang

AU - Duong, Hien T

AU - Laurent, Sophie

AU - Elst, Luce Vander

AU - Muller, Robert N

AU - Lowe, Andrew B.

AU - Davis, Thomas P

AU - Boyer, Cyrille

PY - 2012/10/28

Y1 - 2012/10/28

N2 - We present a new synthetic strategy to produce Gd(iii)-decorated gold nanoparticles (AuNPs) for potential use as bimodal contrast agents (CA) for computed X-ray tomography (CT) and magnetic resonance imaging (MRI). The hybrid AuNPs exhibit high molar relaxivities (>12000 mM -1 s -1 per particle), indicative of highly efficient CT/MRI CAs.

AB - We present a new synthetic strategy to produce Gd(iii)-decorated gold nanoparticles (AuNPs) for potential use as bimodal contrast agents (CA) for computed X-ray tomography (CT) and magnetic resonance imaging (MRI). The hybrid AuNPs exhibit high molar relaxivities (>12000 mM -1 s -1 per particle), indicative of highly efficient CT/MRI CAs.

UR - http://www.scopus.com/inward/record.url?scp=84866984653&partnerID=8YFLogxK

U2 - 10.1039/c2jm34999j

DO - 10.1039/c2jm34999j

M3 - Article

AN - SCOPUS:84866984653

SN - 0959-9428

VL - 22

SP - 21382

EP - 21386

JO - Journal of Materials Chemistry

JF - Journal of Materials Chemistry

IS - 40

ER -

Polymer-gold nanohybrids with potential use in bimodal MRI/CT: enhancing the relaxometric properties of Gd(III) complexes

Abstract

Access to Document

Other files and links

Cite this