Polymer-gold nanohybrids with potential use in bimodal MRI/CT: enhancing the relaxometric properties of Gd(III) complexes

Mariana Beija, Yang Li, Hien T Duong, Sophie Laurent, Luce Vander Elst, Robert N Muller, Andrew B. Lowe, Thomas P Davis, Cyrille Boyer

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36 Citations (Scopus)


We present a new synthetic strategy to produce Gd(iii)-decorated gold nanoparticles (AuNPs) for potential use as bimodal contrast agents (CA) for computed X-ray tomography (CT) and magnetic resonance imaging (MRI). The hybrid AuNPs exhibit high molar relaxivities (>12000 mM -1 s -1 per particle), indicative of highly efficient CT/MRI CAs. 

Original languageEnglish
Pages (from-to)21382-21386
Number of pages5
JournalJournal of Materials Chemistry
Issue number40
Publication statusPublished - 28 Oct 2012
Externally publishedYes

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