TY - JOUR
T1 - Polycystic Ovary Syndrome, Obesity, and Pregnancy
AU - Joham, Anju E.
AU - Palomba, Stefano
AU - Hart, Roger
PY - 2016/2/8
Y1 - 2016/2/8
N2 - Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting up to one in five reproductive-aged women. It is underpinned by insulin resistance and hyperandrogenism and is associated with metabolic, reproductive, and psychological features. Women with PCOS have higher rates of obesity and central adiposity compared with women without PCOS, and weight strongly influences prevalence and clinical severity of PCOS. Women with PCOS may have subfertility and women should be aware of factors affecting fertility, in particular the impact of obesity and age. Once pregnant, women with PCOS have significantly increased risk of pregnancy-related complications including gestational diabetes, hypertensive disorders, premature delivery, and delivery by cesarean section. The offspring of women with PCOS may have increased risk of congenital abnormalities and hospitalization in childhood. Clinicians should be aware of the increased risk and screen, prevent, and manage accordingly.
AB - Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting up to one in five reproductive-aged women. It is underpinned by insulin resistance and hyperandrogenism and is associated with metabolic, reproductive, and psychological features. Women with PCOS have higher rates of obesity and central adiposity compared with women without PCOS, and weight strongly influences prevalence and clinical severity of PCOS. Women with PCOS may have subfertility and women should be aware of factors affecting fertility, in particular the impact of obesity and age. Once pregnant, women with PCOS have significantly increased risk of pregnancy-related complications including gestational diabetes, hypertensive disorders, premature delivery, and delivery by cesarean section. The offspring of women with PCOS may have increased risk of congenital abnormalities and hospitalization in childhood. Clinicians should be aware of the increased risk and screen, prevent, and manage accordingly.
KW - obesity
KW - PCOS
KW - pregnancy complications
UR - http://www.scopus.com/inward/record.url?scp=84959149014&partnerID=8YFLogxK
U2 - 10.1055/s-0035-1571195
DO - 10.1055/s-0035-1571195
M3 - Article
C2 - 26854709
AN - SCOPUS:84959149014
SN - 1526-8004
VL - 34
SP - 93
EP - 101
JO - Seminars in Reproductive Medicine
JF - Seminars in Reproductive Medicine
IS - 2
ER -