Abstract
A new near-infrared light-controlled drug delivery system based on caged gold nanorods (CGNRs) is demonstrated. The loading and release process of drug payloads into/from CGNR nanocarriers were systematically investigated. The drug-loaded CGNR constructs could enable combined chemotherapy and photo-thermal effects in killing tumor cells upon light irradiation, therefore, enhance the killing efficiency. In conjunction with visibility under quenching-free dark-field imaging, CGNRs may serve as multifunctional theranostic reagents towards cancer diagnostics and therapeutics.
| Original language | English |
|---|---|
| Pages (from-to) | 14388 - 14393 |
| Number of pages | 6 |
| Journal | Nanoscale |
| Volume | 6 |
| Issue number | 23 |
| DOIs | |
| Publication status | Published - 2014 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Equipment
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Monash Centre for Electron Microscopy (MCEM)
Sorrell, F. (Manager) & Miller, P. (Manager)
Office of the Vice-Provost (Research and Research Infrastructure)Facility/equipment: Facility
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