Plasmonic caged gold nanorods for near-infrared light controlled drug delivery

Wei Xiong, Romiza Rehana Mazid, Lim Wei Yap, Xinyong Li, Wenlong Cheng

Research output: Contribution to journalArticleResearchpeer-review

41 Citations (Scopus)

Abstract

A new near-infrared light-controlled drug delivery system based on caged gold nanorods (CGNRs) is demonstrated. The loading and release process of drug payloads into/from CGNR nanocarriers were systematically investigated. The drug-loaded CGNR constructs could enable combined chemotherapy and photo-thermal effects in killing tumor cells upon light irradiation, therefore, enhance the killing efficiency. In conjunction with visibility under quenching-free dark-field imaging, CGNRs may serve as multifunctional theranostic reagents towards cancer diagnostics and therapeutics.
Original languageEnglish
Pages (from-to)14388 - 14393
Number of pages6
JournalNanoscale
Volume6
Issue number23
DOIs
Publication statusPublished - 2014

Cite this