TY - JOUR
T1 - Plasmodium falciparum rosette formation is uncommon in isolates from pregnant women
AU - Rogerson, Stephen J.
AU - Beeson, James G.
AU - Mhango, Chisale G.
AU - Dzinjalamala, Fraction K.
AU - Molyneux, Malcolm E.
PY - 2000/1/1
Y1 - 2000/1/1
N2 - We examined the formation of Plasmodium falciparum erythrocyte rosettes using parasite isolates from placental or peripheral blood of pregnant Malawian women and from peripheral blood of children. Five of 23 placental isolates, 23 of 38 maternal peripheral isolates, and 136 of 139 child peripheral isolates formed rosettes. Placental isolates formed fewer rosettes than maternal isolates (range, 0 to 7.5% versus 0 to 33.5%; P = 0.002), and both formed fewer rosettes than isolates cultured from children (range, 0 to 56%; P < 0.0001). Rosette formation is common in infections of children but uncommon in pregnancy and rarely detected in placental isolates.
AB - We examined the formation of Plasmodium falciparum erythrocyte rosettes using parasite isolates from placental or peripheral blood of pregnant Malawian women and from peripheral blood of children. Five of 23 placental isolates, 23 of 38 maternal peripheral isolates, and 136 of 139 child peripheral isolates formed rosettes. Placental isolates formed fewer rosettes than maternal isolates (range, 0 to 7.5% versus 0 to 33.5%; P = 0.002), and both formed fewer rosettes than isolates cultured from children (range, 0 to 56%; P < 0.0001). Rosette formation is common in infections of children but uncommon in pregnancy and rarely detected in placental isolates.
UR - http://www.scopus.com/inward/record.url?scp=0033975742&partnerID=8YFLogxK
U2 - 10.1128/IAI.68.1.391-393.2000
DO - 10.1128/IAI.68.1.391-393.2000
M3 - Article
C2 - 10603414
AN - SCOPUS:0033975742
SN - 0019-9567
VL - 68
SP - 391
EP - 393
JO - Infection and Immunity
JF - Infection and Immunity
IS - 1
ER -
