Plasmid Incidence Rate and Conjugative Chloramphenicol and Tetracycline Resistance Plasmids in Malaysian Isolates of Salmonella typhi

Maude Phipps; Tikki Pang; Chong Lek Koh; Savithri Puthucheary

doi:10.1111/j.1348-0421.1991.tb01543.x

Plasmid Incidence Rate and Conjugative Chloramphenicol and Tetracycline Resistance Plasmids in Malaysian Isolates of Salmonella typhi

Maude Phipps, Tikki Pang, Chong Lek Koh, Savithri Puthucheary

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Abstract

Seven (6.1%) of 115 strains of Salmonella typhi isolated from Malaysian patients harbored a single large plasmid of 71 to 166 mD. Two of the seven plasmid-bearing strains were resistant to chloramphenicol (Cm) and tetracycline (Tc) and they transferred Cm and Tc resistance traits to Escherichia coli K12 at frequencies from 1.6 X 10 ⁷ to 1.9 x 10 ⁶. Agarose gel electrophoresis provided evidence that the resistance traits were cotransferred on a conjugative plasmid. The significance and importance of these results are discussed.

Original language	English
Pages (from-to)	1073-1084
Number of pages	12
Journal	Microbiology and Immunology
Volume	35
Issue number	2
DOIs	https://doi.org/10.1111/j.1348-0421.1991.tb01543.x
Publication status	Published - 1991
Externally published	Yes

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title = "Plasmid Incidence Rate and Conjugative Chloramphenicol and Tetracycline Resistance Plasmids in Malaysian Isolates of Salmonella typhi",

abstract = "Seven (6.1%) of 115 strains of Salmonella typhi isolated from Malaysian patients harbored a single large plasmid of 71 to 166 mD. Two of the seven plasmid-bearing strains were resistant to chloramphenicol (Cm) and tetracycline (Tc) and they transferred Cm and Tc resistance traits to Escherichia coli K12 at frequencies from 1.6 X 10 7 to 1.9 x 10 6. Agarose gel electrophoresis provided evidence that the resistance traits were cotransferred on a conjugative plasmid. The significance and importance of these results are discussed.",

author = "Maude Phipps and Tikki Pang and Koh, {Chong Lek} and Savithri Puthucheary",

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AU - Phipps, Maude

AU - Pang, Tikki

AU - Koh, Chong Lek

AU - Puthucheary, Savithri

PY - 1991

Y1 - 1991

N2 - Seven (6.1%) of 115 strains of Salmonella typhi isolated from Malaysian patients harbored a single large plasmid of 71 to 166 mD. Two of the seven plasmid-bearing strains were resistant to chloramphenicol (Cm) and tetracycline (Tc) and they transferred Cm and Tc resistance traits to Escherichia coli K12 at frequencies from 1.6 X 10 7 to 1.9 x 10 6. Agarose gel electrophoresis provided evidence that the resistance traits were cotransferred on a conjugative plasmid. The significance and importance of these results are discussed.

AB - Seven (6.1%) of 115 strains of Salmonella typhi isolated from Malaysian patients harbored a single large plasmid of 71 to 166 mD. Two of the seven plasmid-bearing strains were resistant to chloramphenicol (Cm) and tetracycline (Tc) and they transferred Cm and Tc resistance traits to Escherichia coli K12 at frequencies from 1.6 X 10 7 to 1.9 x 10 6. Agarose gel electrophoresis provided evidence that the resistance traits were cotransferred on a conjugative plasmid. The significance and importance of these results are discussed.

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U2 - 10.1111/j.1348-0421.1991.tb01543.x

DO - 10.1111/j.1348-0421.1991.tb01543.x

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IS - 2

ER -

Plasmid Incidence Rate and Conjugative Chloramphenicol and Tetracycline Resistance Plasmids in Malaysian Isolates of Salmonella typhi

Abstract

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