Abstract
Seven (6.1%) of 115 strains of Salmonella typhi isolated from Malaysian patients harbored a single large plasmid of 71 to 166 mD. Two of the seven plasmid-bearing strains were resistant to chloramphenicol (Cm) and tetracycline (Tc) and they transferred Cm and Tc resistance traits to Escherichia coli K12 at frequencies from 1.6 X 10 7 to 1.9 x 10 6. Agarose gel electrophoresis provided evidence that the resistance traits were cotransferred on a conjugative plasmid. The significance and importance of these results are discussed.
Original language | English |
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Pages (from-to) | 1073-1084 |
Number of pages | 12 |
Journal | Microbiology and Immunology |
Volume | 35 |
Issue number | 2 |
DOIs | |
Publication status | Published - 1991 |
Externally published | Yes |