Plasma lysophosphatidylcholine levels are reduced in obesity and type 2 diabetes

Melissa Barber; Steve Risis; Christine Yang; Peter J Meikle; Margaret Staples; Mark A Febbraio; Clinton Bruce

doi:10.1371/journal.pone.0041456

Plasma lysophosphatidylcholine levels are reduced in obesity and type 2 diabetes

Melissa Barber, Steve Risis, Christine Yang, Peter J Meikle, Margaret Staples, Mark A Febbraio, Clinton Bruce

Research output: Contribution to journal › Article › Research › peer-review

292 Citations (Scopus)

Abstract

Irrespective of species, our lipidomic profiling revealed a generalized decrease in circulating LPC species in states of obesity. Moreover, our data indicate that diet and adiposity, rather than insulin resistance or diabetes per se, play an important role in altering the plasma LPC profile.

Original language	English
Article number	e41456
Number of pages	12
Journal	PLoS ONE
Volume	7
Issue number	7
DOIs	https://doi.org/10.1371/journal.pone.0041456
Publication status	Published - 2012

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title = "Plasma lysophosphatidylcholine levels are reduced in obesity and type 2 diabetes",

abstract = "Irrespective of species, our lipidomic profiling revealed a generalized decrease in circulating LPC species in states of obesity. Moreover, our data indicate that diet and adiposity, rather than insulin resistance or diabetes per se, play an important role in altering the plasma LPC profile.",

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AU - Barber, Melissa

AU - Risis, Steve

AU - Yang, Christine

AU - Meikle, Peter J

AU - Staples, Margaret

AU - Febbraio, Mark A

AU - Bruce, Clinton

PY - 2012

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Plasma lysophosphatidylcholine levels are reduced in obesity and type 2 diabetes

Abstract

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