Abstract
1. A simple, rapid and specific gas chromatographic method for the measurement of plasma carbamazepine concentration is presented. 2. The extraction is a single step method, and the drug is measured by derivatization using on column methylation and standard instrumentation. 3. Other anticonvulsant agents do not co‐extract. Other drugs do not interfere in the chromatogram. 4. Stability, recovery and reproducibility make this procedure suitable for routine carbamazepine measurements.
Original language | English |
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Pages (from-to) | 497-501 |
Number of pages | 5 |
Journal | Clinical and Experimental Pharmacology and Physiology |
Volume | 3 |
Issue number | 5 |
DOIs | |
Publication status | Published - Oct 1976 |
Externally published | Yes |
Keywords
- carbamazepine
- GLC
- plasma.