TY - JOUR
T1 - Pioglitazone treatment enhances the sympathetic nervous system response to oral carbohydrate load in obese individuals with metabolic syndrome
AU - Straznicky, Nora
AU - Grima, Mariee
AU - Sari, Carolina I
AU - Eikelis, Nina
AU - Lambert, Gavin William
AU - Nestel, Paul John
AU - Richards, Katrina
AU - Dixon, John
AU - Schlaich, Markus Peter
AU - Lambert, Elisabeth
PY - 2015
Y1 - 2015
N2 - Insulin resistance is associated with blunted sympathetic nervous system (SNS) response to carbohydrate ingestion which may contribute to postprandial hypotension and impaired body weight homeostasis.
This study was conducted to examine the effects of harmacological insulin sensitization on whole-body norepinephrine kinetics during a standard 75-g oral glucose tolerance test (OGTT) in obese, insulin resistant subjects with metabolic syndrome.
AB - Insulin resistance is associated with blunted sympathetic nervous system (SNS) response to carbohydrate ingestion which may contribute to postprandial hypotension and impaired body weight homeostasis.
This study was conducted to examine the effects of harmacological insulin sensitization on whole-body norepinephrine kinetics during a standard 75-g oral glucose tolerance test (OGTT) in obese, insulin resistant subjects with metabolic syndrome.
UR - http://www.sciencedirect.com/science/article/pii/S0026049515000803
U2 - 10.1016/j.metabol.2015.03.006
DO - 10.1016/j.metabol.2015.03.006
M3 - Article
SN - 0026-0495
VL - 64
SP - 797
EP - 803
JO - Metabolism: Clinical and Experimental
JF - Metabolism: Clinical and Experimental
IS - 7
ER -