Pioglitazone treatment enhances the sympathetic nervous system response to oral carbohydrate load in obese individuals with metabolic syndrome

Nora Straznicky, Mariee Grima, Carolina I Sari, Nina Eikelis, Gavin William Lambert, Paul John Nestel, Katrina Richards, John Dixon, Markus Peter Schlaich, Elisabeth Lambert

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6 Citations (Scopus)


Insulin resistance is associated with blunted sympathetic nervous system (SNS) response to carbohydrate ingestion which may contribute to postprandial hypotension and impaired body weight homeostasis. This study was conducted to examine the effects of harmacological insulin sensitization on whole-body norepinephrine kinetics during a standard 75-g oral glucose tolerance test (OGTT) in obese, insulin resistant subjects with metabolic syndrome.
Original languageEnglish
Pages (from-to)797 - 803
Number of pages7
JournalMetabolism: Clinical and Experimental
Issue number7
Publication statusPublished - 2015

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