Pilot Validation of Ambulatory Activity Monitors for Sleep Measurement in Huntington's Disease Gene Carriers

Svetlana Maskevich, Ria Jumabhoy, Pierre D.M. Dao, Julie C. Stout, Sean P.A. Drummond

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Sleep disturbance occurs early in Huntington's disease (HD). Consumer- and research-grade activity monitors may enable routine assessment of sleep disturbances in HD.We compared Actiwatch Spectrum Pro, Jawbone UP2 and Fitbit One to the gold standard, polysomnography, in four late presymptomatic and three early HD participants. Compared to polysomnography, all ambulatory monitors overestimated total sleep time by >60 minutes and sleep efficiency by -15%. Thus, for assessment of specific sleep parameters in HD, none of the activity monitors are sufficiently accurate to replace polysomnography, although they may be sufficient for estimating overall sleep-wake patterns. Larger sample replication is required.

Original languageEnglish
Pages (from-to)249-253
Number of pages5
JournalJournal of Huntington's Disease
Volume6
Issue number3
DOIs
Publication statusPublished - 29 Sep 2017

Keywords

  • actigraphy
  • ambulatory monitoring
  • Huntington's disease
  • sleep
  • validation

Cite this

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title = "Pilot Validation of Ambulatory Activity Monitors for Sleep Measurement in Huntington's Disease Gene Carriers",
abstract = "Sleep disturbance occurs early in Huntington's disease (HD). Consumer- and research-grade activity monitors may enable routine assessment of sleep disturbances in HD.We compared Actiwatch Spectrum Pro, Jawbone UP2 and Fitbit One to the gold standard, polysomnography, in four late presymptomatic and three early HD participants. Compared to polysomnography, all ambulatory monitors overestimated total sleep time by >60 minutes and sleep efficiency by -15{\%}. Thus, for assessment of specific sleep parameters in HD, none of the activity monitors are sufficiently accurate to replace polysomnography, although they may be sufficient for estimating overall sleep-wake patterns. Larger sample replication is required.",
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Pilot Validation of Ambulatory Activity Monitors for Sleep Measurement in Huntington's Disease Gene Carriers. / Maskevich, Svetlana; Jumabhoy, Ria; Dao, Pierre D.M.; Stout, Julie C.; Drummond, Sean P.A.

In: Journal of Huntington's Disease, Vol. 6, No. 3, 29.09.2017, p. 249-253.

Research output: Contribution to journalArticleResearchpeer-review

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AU - Drummond, Sean P.A.

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