Pills of PTEN? in and out for tumor suppression

Antonella Papa; Ming Chen; Pier Paolo Pandolfi

doi:10.1038/cr.2013.103

Pills of PTEN? in and out for tumor suppression

Antonella Papa, Ming Chen, Pier Paolo Pandolfi

Research output: Contribution to journal › Article › Other › peer-review

10 Citations (Scopus)

Abstract

The tumor-suppressive activity of PTEN has always been attributed to its endogenous intracellular function. Recently two different groups have demonstrated that PTEN is secreted/exported into the extracellular environment for uptake by recipient cells, and functions as a tumor suppressor in a cell non-autonomous manner.

Original language	English
Pages (from-to)	1155-1156
Number of pages	2
Journal	Cell Research
Volume	23
Issue number	10
DOIs	https://doi.org/10.1038/cr.2013.103
Publication status	Published - Oct 2013
Externally published	Yes

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10.1038/cr.2013.103

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title = "Pills of PTEN? in and out for tumor suppression",

abstract = "The tumor-suppressive activity of PTEN has always been attributed to its endogenous intracellular function. Recently two different groups have demonstrated that PTEN is secreted/exported into the extracellular environment for uptake by recipient cells, and functions as a tumor suppressor in a cell non-autonomous manner.",

author = "Antonella Papa and Ming Chen and Pandolfi, {Pier Paolo}",

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Pills of PTEN? in and out for tumor suppression

Abstract

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