TY - JOUR
T1 - Phytochemical screening and antioxidant activity of Cananga odorata extract
AU - Jiea, Chew Khe
AU - Fuloria, Shivkanya
AU - Subrimanyan, Vetriselvan
AU - Sekar, Mahendran
AU - Sathasivam, Kathiresan V.
AU - Kayarohanam, Saminathan
AU - Wu, Yuan Seng
AU - Velaga, Venkata Sathya Saiappala Raju
AU - Janakiraman, Ashok Kumar
AU - Maziz, Mohammad Nazmul Hasan
AU - Fuloria, Neeraj Kumar
N1 - Funding Information:
We gratefully appreciate AIMST University, Malaysia; MAHSA University, Malaysia; University of Science and Technology, Sultanate Oman, Muscat; Universiti Kuala Lumpur, Malaysia; and Gurukul Kangri (Deemed to be University), Haridwar-249404, India for their support for successful completion of this study.
Publisher Copyright:
© RJPT All right reserved.
PY - 2022/3
Y1 - 2022/3
N2 - Plants are the natural source for the antioxidants from plants source is boon for the investigators. Present study was aimed to study the antioxidant activity and phytochemical screening of Cananga odorata (Lam.) Hook. f. & Thomson extract. Study involved preparation hydroalcoholic extract of Cananga odorata leaves (HECOL) using maceration method, followed by its phytochemical screening and antioxidant activity. The HECOL was subjected to determination of total phenolic content (TPC) and total flavonoid content (TFC), and DPPH (1,1-Diphenyl-2-picryl hydrazyl) radical scavenging assay for determination of antioxidant activity. Maceration of C. odorata using hydroalcoholic solvent offered dark brown colored HECOL. Phytochemical screening of HECOL exhibited presence of carbohydrates, mucilage, fats and oils, volatile oils, anthraquinone glycosides, flavonoids, alkaloids, tannins and phenolic compounds. For TPC the gallic acid equivalent of HECOL was found to be 0.507 mg GAE/g. Whereas for TFC, the rutin equivalent of HECOL was found to be 0.2224mg RE/g. The antioxidant activity of HECOL was estimated to be 120.44μg/ml (IC50). Based on the experimental results, present study concludes that HECOL possess the significant antioxidant potential. This study also recommends that antioxidant activity potential of C. odorata leaves should be further explored using different solvent extracts.
AB - Plants are the natural source for the antioxidants from plants source is boon for the investigators. Present study was aimed to study the antioxidant activity and phytochemical screening of Cananga odorata (Lam.) Hook. f. & Thomson extract. Study involved preparation hydroalcoholic extract of Cananga odorata leaves (HECOL) using maceration method, followed by its phytochemical screening and antioxidant activity. The HECOL was subjected to determination of total phenolic content (TPC) and total flavonoid content (TFC), and DPPH (1,1-Diphenyl-2-picryl hydrazyl) radical scavenging assay for determination of antioxidant activity. Maceration of C. odorata using hydroalcoholic solvent offered dark brown colored HECOL. Phytochemical screening of HECOL exhibited presence of carbohydrates, mucilage, fats and oils, volatile oils, anthraquinone glycosides, flavonoids, alkaloids, tannins and phenolic compounds. For TPC the gallic acid equivalent of HECOL was found to be 0.507 mg GAE/g. Whereas for TFC, the rutin equivalent of HECOL was found to be 0.2224mg RE/g. The antioxidant activity of HECOL was estimated to be 120.44μg/ml (IC50). Based on the experimental results, present study concludes that HECOL possess the significant antioxidant potential. This study also recommends that antioxidant activity potential of C. odorata leaves should be further explored using different solvent extracts.
KW - antioxidant activity
KW - Canaga odorata
KW - gallic acid
KW - total flavonoid content
KW - total phenolic content
UR - http://www.scopus.com/inward/record.url?scp=85128736780&partnerID=8YFLogxK
U2 - 10.52711/0974-360X.2022.00205
DO - 10.52711/0974-360X.2022.00205
M3 - Article
AN - SCOPUS:85128736780
SN - 0974-3618
VL - 15
SP - 1230
EP - 1234
JO - Research Journal of Pharmacy and Technology
JF - Research Journal of Pharmacy and Technology
IS - 3
ER -