Physiological control

Michael C. Stevens, Andrew Stephens, Abdul Hakeem H. AlOmari, Francesco Moscato

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

9 Citations (Scopus)


Rotary left ventricular assist devices (LVADs) have greatly improved the outcomes and quality of life of patients with heart failure. However, rotary LVADs, when operated at a set speed, may result in over- or underpumping, leading to ventricular suction or venous congestion. This chapter discusses physiological control of rotary LVADs, systems that automatically adjust LVAD output based on changes in the state of the circulatory system. Such systems aim to adjust speed based on measurements (or estimation) of hemodynamic variables such as flow, pressure, or a combination of these. This chapter also summarizes methods of measuring and estimating hemodynamic variables that can be used to implement these systems in clinic. While significant development in this field has occurred over the last two decades, physiological control systems are still yet to be applied clinically.

Original languageEnglish
Title of host publicationMechanical Circulatory and Respiratory Support
EditorsShaun D. Gregory, Michael C. Stevens, John F. Fraser
Place of PublicationLondon UK
PublisherAcademic Press
Number of pages31
ISBN (Electronic)9780128104927
ISBN (Print)9780128104910
Publication statusPublished - 2018
Externally publishedYes


  • Estimation
  • Feature extraction
  • Physiological control
  • Sensors
  • Ventricular assist devices

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