Physiological control

Michael C. Stevens; Andrew Stephens; Abdul Hakeem H. AlOmari; Francesco Moscato

doi:10.1016/B978-0-12-810491-0.00020-5

Physiological control

Michael C. Stevens, Andrew Stephens, Abdul Hakeem H. AlOmari, Francesco Moscato

Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review

15 Citations (Scopus)

Abstract

Rotary left ventricular assist devices (LVADs) have greatly improved the outcomes and quality of life of patients with heart failure. However, rotary LVADs, when operated at a set speed, may result in over- or underpumping, leading to ventricular suction or venous congestion. This chapter discusses physiological control of rotary LVADs, systems that automatically adjust LVAD output based on changes in the state of the circulatory system. Such systems aim to adjust speed based on measurements (or estimation) of hemodynamic variables such as flow, pressure, or a combination of these. This chapter also summarizes methods of measuring and estimating hemodynamic variables that can be used to implement these systems in clinic. While significant development in this field has occurred over the last two decades, physiological control systems are still yet to be applied clinically.

Original language	English
Title of host publication	Mechanical Circulatory and Respiratory Support
Editors	Shaun D. Gregory, Michael C. Stevens, John F. Fraser
Place of Publication	London UK
Publisher	Academic Press
Chapter	20
Pages	627-657
Number of pages	31
ISBN (Electronic)	9780128104927
ISBN (Print)	9780128104910
DOIs	https://doi.org/10.1016/B978-0-12-810491-0.00020-5
Publication status	Published - 2018
Externally published	Yes

Keywords

Estimation
Feature extraction
Physiological control
Sensors
Ventricular assist devices

Access to Document

10.1016/B978-0-12-810491-0.00020-5

Cite this

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abstract = "Rotary left ventricular assist devices (LVADs) have greatly improved the outcomes and quality of life of patients with heart failure. However, rotary LVADs, when operated at a set speed, may result in over- or underpumping, leading to ventricular suction or venous congestion. This chapter discusses physiological control of rotary LVADs, systems that automatically adjust LVAD output based on changes in the state of the circulatory system. Such systems aim to adjust speed based on measurements (or estimation) of hemodynamic variables such as flow, pressure, or a combination of these. This chapter also summarizes methods of measuring and estimating hemodynamic variables that can be used to implement these systems in clinic. While significant development in this field has occurred over the last two decades, physiological control systems are still yet to be applied clinically.",

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AU - Stevens, Michael C.

AU - Stephens, Andrew

AU - AlOmari, Abdul Hakeem H.

AU - Moscato, Francesco

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N2 - Rotary left ventricular assist devices (LVADs) have greatly improved the outcomes and quality of life of patients with heart failure. However, rotary LVADs, when operated at a set speed, may result in over- or underpumping, leading to ventricular suction or venous congestion. This chapter discusses physiological control of rotary LVADs, systems that automatically adjust LVAD output based on changes in the state of the circulatory system. Such systems aim to adjust speed based on measurements (or estimation) of hemodynamic variables such as flow, pressure, or a combination of these. This chapter also summarizes methods of measuring and estimating hemodynamic variables that can be used to implement these systems in clinic. While significant development in this field has occurred over the last two decades, physiological control systems are still yet to be applied clinically.

AB - Rotary left ventricular assist devices (LVADs) have greatly improved the outcomes and quality of life of patients with heart failure. However, rotary LVADs, when operated at a set speed, may result in over- or underpumping, leading to ventricular suction or venous congestion. This chapter discusses physiological control of rotary LVADs, systems that automatically adjust LVAD output based on changes in the state of the circulatory system. Such systems aim to adjust speed based on measurements (or estimation) of hemodynamic variables such as flow, pressure, or a combination of these. This chapter also summarizes methods of measuring and estimating hemodynamic variables that can be used to implement these systems in clinic. While significant development in this field has occurred over the last two decades, physiological control systems are still yet to be applied clinically.

KW - Estimation

KW - Feature extraction

KW - Physiological control

KW - Sensors

KW - Ventricular assist devices

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U2 - 10.1016/B978-0-12-810491-0.00020-5

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M3 - Chapter (Book)

SN - 9780128104910

SP - 627

EP - 657

BT - Mechanical Circulatory and Respiratory Support

A2 - Gregory, Shaun D.

A2 - Stevens, Michael C.

A2 - Fraser, John F.

PB - Academic Press

CY - London UK

ER -

Physiological control

Abstract

Keywords

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