Physicochemical properties, in vitro antioxidant activities and inhibitory potential against α-glucosidase of polysaccharides from ampelopsis grossedentata leaves and stems

Yuefei Wang, Xiaoying Bian, Jinhyouch Park, Le Ying, Lisheng Qian, Ping Xu

Research output: Contribution to journalArticleResearchpeer-review

23 Citations (Scopus)

Abstract

In the present study, polysaccharides named ALPS and ASPS were isolated from Ampelopsis grossedentata leaves and stems, respectively. Physicochemical properties, in vitro antioxidant activities and the inhibitory effects on α-glucosidase of ALPS and ASPS were investigated. It was found that both ALPS and ASPS were acid protein-bound heteropolysaccharides, although with considerably different chemical composition and molecular weight distribution. Meanwhile, in comparison with ALPS, ASPS exhibited stronger antioxidant activity and inhibitory potential against α-glucosidase according to the in vitro evaluation. Moreover, our results suggested that protein and uronic acid might, at least partly, contribute positively to the biological behavior of ALPS and ASPS.

Original languageEnglish
Pages (from-to)7762-7772
Number of pages11
JournalMolecules
Volume16
Issue number9
DOIs
Publication statusPublished - Sept 2011
Externally publishedYes

Keywords

  • α-glucosidase inhibition
  • Ampelopsis grossedentata
  • Antioxidant activities
  • Physicochemical properties
  • Polysaccharides

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