The use of dynamic contrast agent-enhanced magnetic resonance imaging (MRI) can provide insight into hemodynamic processes not detectable during static conventional contrast-enhanced MR techniques. These additional data may allow further refinement of differential diagnoses focusing on interpretation in terms of microvascular physiology. The dominant dynamic gadolinium (Gd)-enhanced bolus injection MR techniques currently utilized in brain imaging are (1) T1-weighted dynamic contrast-enhanced (DCE) and (2) T2/T2*-weighted dynamic susceptibility contrast (DSC) imaging. This chapter will provide an overview of general physical principles of these techniques.
|Title of host publication||Functional Neuroradiology|
|Subtitle of host publication||Principles and Clinical Applications|
|Number of pages||7|
|Publication status||Published - 1 Jan 2012|