Physical principles of MR perfusion and permeability imaging: Gadolinium bolus technique

Mark S. Shiroishi, Saulo Lacerda, Xiaoli Tang, Naira Muradyan, Timothy P.L. Roberts, Meng Law

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

2 Citations (Scopus)

Abstract

The use of dynamic contrast agent-enhanced magnetic resonance imaging (MRI) can provide insight into hemodynamic processes not detectable during static conventional contrast-enhanced MR techniques. These additional data may allow further refinement of differential diagnoses focusing on interpretation in terms of microvascular physiology. The dominant dynamic gadolinium (Gd)-enhanced bolus injection MR techniques currently utilized in brain imaging are (1) T1-weighted dynamic contrast-enhanced (DCE) and (2) T2/T2*-weighted dynamic susceptibility contrast (DSC) imaging. This chapter will provide an overview of general physical principles of these techniques.

Original languageEnglish
Title of host publicationFunctional Neuroradiology
Subtitle of host publicationPrinciples and Clinical Applications
PublisherHumana Press
Pages53-59
Number of pages7
ISBN (Electronic)9781441903457
ISBN (Print)9781441903433
DOIs
Publication statusPublished - 1 Jan 2012
Externally publishedYes

Cite this

Shiroishi, M. S., Lacerda, S., Tang, X., Muradyan, N., Roberts, T. P. L., & Law, M. (2012). Physical principles of MR perfusion and permeability imaging: Gadolinium bolus technique. In Functional Neuroradiology: Principles and Clinical Applications (pp. 53-59). Humana Press. https://doi.org/10.1007/978-1-4419-0345-7_3