Photonic lab-on-a-chip device with UV light responsive smart surfaces

Matthias Duebner; Victor J. Cadarso; Celestino Padeste

doi:10.1109/TRANSDUCERS.2017.7994513

Photonic lab-on-a-chip device with UV light responsive smart surfaces

Matthias Duebner, Victor J. Cadarso, Celestino Padeste

Mechanical & Aerospace Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › Research

Abstract

A novel lab-on-a-chip (LoC) device based on the combination of an optofluidic component and a polymeric substrate with a smart surface reacting on UV light is presented for the first time. In the dark or under visible light, the surface containing an enzyme fragment is almost inert and visible (VIS) light (i.e. @ 635 nm) propagating through the optofluidic device is mostly unaffected. When the device is exposed to UV light, the smart surface consisting of spiropyran-functionalized polymer brushes reacts with increased hydrophilicity. As a consequence, the polymer brushes are swelling, enhancing the access of reagents to the enclosed enzyme. The enzymatic reaction yields a blue reaction product causing increased absorbance at 635 nm. Here, we demonstrate both the integration of the optofluidic component and the smart surface into a photonic LoC device, its behavior and performance and the reversible nature of the UV activation.

Original language	English
Title of host publication	2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS 2017)
Subtitle of host publication	Kaohsiung, Taiwan 18 – 22 June 2017
Editors	Shuichi Shoji
Place of Publication	Piscataway NJ USA
Publisher	IEEE, Institute of Electrical and Electronics Engineers
Pages	2199-2202
Number of pages	4
ISBN (Electronic)	9781538627327
ISBN (Print)	9781538627334
DOIs	https://doi.org/10.1109/TRANSDUCERS.2017.7994513
Publication status	Published - 2017
Event	International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers 2017) - Kaohsiung Exhibition Center, Kaohsiung, Taiwan Duration: 18 Jun 2017 → 22 Jun 2017 Conference number: 19th https://www.ieee.org/conferences_events/conferences/conferencedetails/index.html?Conf_ID=41128

Conference

Conference	International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers 2017)
Abbreviated title	Transducers 2017
Country/Territory	Taiwan
City	Kaohsiung
Period	18/06/17 → 22/06/17
Internet address	https://www.ieee.org/conferences_events/conferences/conferencedetails/index.html?Conf_ID=41128

Keywords

optical activation
Photonic Lab-on-a-chip
polymer brushes
smart surface

Access to Document

10.1109/TRANSDUCERS.2017.7994513

Cite this

Duebner, M., Cadarso, V. J., & Padeste, C. (2017). Photonic lab-on-a-chip device with UV light responsive smart surfaces. In S. Shoji (Ed.), 2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS 2017) : Kaohsiung, Taiwan 18 – 22 June 2017 (pp. 2199-2202). IEEE, Institute of Electrical and Electronics Engineers. https://doi.org/10.1109/TRANSDUCERS.2017.7994513

Duebner, Matthias ; Cadarso, Victor J. ; Padeste, Celestino. / Photonic lab-on-a-chip device with UV light responsive smart surfaces. 2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS 2017) : Kaohsiung, Taiwan 18 – 22 June 2017. editor / Shuichi Shoji. Piscataway NJ USA : IEEE, Institute of Electrical and Electronics Engineers, 2017. pp. 2199-2202

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abstract = "A novel lab-on-a-chip (LoC) device based on the combination of an optofluidic component and a polymeric substrate with a smart surface reacting on UV light is presented for the first time. In the dark or under visible light, the surface containing an enzyme fragment is almost inert and visible (VIS) light (i.e. @ 635 nm) propagating through the optofluidic device is mostly unaffected. When the device is exposed to UV light, the smart surface consisting of spiropyran-functionalized polymer brushes reacts with increased hydrophilicity. As a consequence, the polymer brushes are swelling, enhancing the access of reagents to the enclosed enzyme. The enzymatic reaction yields a blue reaction product causing increased absorbance at 635 nm. Here, we demonstrate both the integration of the optofluidic component and the smart surface into a photonic LoC device, its behavior and performance and the reversible nature of the UV activation.",

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Duebner, M, Cadarso, VJ & Padeste, C 2017, Photonic lab-on-a-chip device with UV light responsive smart surfaces. in S Shoji (ed.), 2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS 2017) : Kaohsiung, Taiwan 18 – 22 June 2017. IEEE, Institute of Electrical and Electronics Engineers, Piscataway NJ USA, pp. 2199-2202, International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers 2017), Kaohsiung, Taiwan, 18/06/17. https://doi.org/10.1109/TRANSDUCERS.2017.7994513

Photonic lab-on-a-chip device with UV light responsive smart surfaces. / Duebner, Matthias; Cadarso, Victor J.; Padeste, Celestino.
2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS 2017) : Kaohsiung, Taiwan 18 – 22 June 2017. ed. / Shuichi Shoji. Piscataway NJ USA: IEEE, Institute of Electrical and Electronics Engineers, 2017. p. 2199-2202.

Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › Research

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AU - Cadarso, Victor J.

AU - Padeste, Celestino

N1 - Conference code: 19th

PY - 2017

Y1 - 2017

N2 - A novel lab-on-a-chip (LoC) device based on the combination of an optofluidic component and a polymeric substrate with a smart surface reacting on UV light is presented for the first time. In the dark or under visible light, the surface containing an enzyme fragment is almost inert and visible (VIS) light (i.e. @ 635 nm) propagating through the optofluidic device is mostly unaffected. When the device is exposed to UV light, the smart surface consisting of spiropyran-functionalized polymer brushes reacts with increased hydrophilicity. As a consequence, the polymer brushes are swelling, enhancing the access of reagents to the enclosed enzyme. The enzymatic reaction yields a blue reaction product causing increased absorbance at 635 nm. Here, we demonstrate both the integration of the optofluidic component and the smart surface into a photonic LoC device, its behavior and performance and the reversible nature of the UV activation.

AB - A novel lab-on-a-chip (LoC) device based on the combination of an optofluidic component and a polymeric substrate with a smart surface reacting on UV light is presented for the first time. In the dark or under visible light, the surface containing an enzyme fragment is almost inert and visible (VIS) light (i.e. @ 635 nm) propagating through the optofluidic device is mostly unaffected. When the device is exposed to UV light, the smart surface consisting of spiropyran-functionalized polymer brushes reacts with increased hydrophilicity. As a consequence, the polymer brushes are swelling, enhancing the access of reagents to the enclosed enzyme. The enzymatic reaction yields a blue reaction product causing increased absorbance at 635 nm. Here, we demonstrate both the integration of the optofluidic component and the smart surface into a photonic LoC device, its behavior and performance and the reversible nature of the UV activation.

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ER -

Duebner M, Cadarso VJ, Padeste C. Photonic lab-on-a-chip device with UV light responsive smart surfaces. In Shoji S, editor, 2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS 2017) : Kaohsiung, Taiwan 18 – 22 June 2017. Piscataway NJ USA: IEEE, Institute of Electrical and Electronics Engineers. 2017. p. 2199-2202 doi: 10.1109/TRANSDUCERS.2017.7994513

Photonic lab-on-a-chip device with UV light responsive smart surfaces

Abstract

Conference

Keywords

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