Photonic lab-on-a-chip device with UV light responsive smart surfaces

Matthias Duebner, Victor J. Cadarso, Celestino Padeste

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearch

Abstract

A novel lab-on-a-chip (LoC) device based on the combination of an optofluidic component and a polymeric substrate with a smart surface reacting on UV light is presented for the first time. In the dark or under visible light, the surface containing an enzyme fragment is almost inert and visible (VIS) light (i.e. @ 635 nm) propagating through the optofluidic device is mostly unaffected. When the device is exposed to UV light, the smart surface consisting of spiropyran-functionalized polymer brushes reacts with increased hydrophilicity. As a consequence, the polymer brushes are swelling, enhancing the access of reagents to the enclosed enzyme. The enzymatic reaction yields a blue reaction product causing increased absorbance at 635 nm. Here, we demonstrate both the integration of the optofluidic component and the smart surface into a photonic LoC device, its behavior and performance and the reversible nature of the UV activation.

Original languageEnglish
Title of host publication2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS 2017)
Subtitle of host publicationKaohsiung, Taiwan 18 – 22 June 2017
EditorsShuichi Shoji
Place of PublicationPiscataway NJ USA
PublisherIEEE, Institute of Electrical and Electronics Engineers
Pages2199-2202
Number of pages4
ISBN (Electronic)9781538627327
ISBN (Print)9781538627334
DOIs
Publication statusPublished - 2017
EventInternational Conference on Solid-State Sensors, Actuators and Microsystems (Transducers 2017) - Kaohsiung Exhibition Center, Kaohsiung, Taiwan
Duration: 18 Jun 201722 Jun 2017
Conference number: 19th
https://www.ieee.org/conferences_events/conferences/conferencedetails/index.html?Conf_ID=41128

Conference

ConferenceInternational Conference on Solid-State Sensors, Actuators and Microsystems (Transducers 2017)
Abbreviated titleTransducers 2017
CountryTaiwan
CityKaohsiung
Period18/06/1722/06/17
Internet address

Keywords

  • optical activation
  • Photonic Lab-on-a-chip
  • polymer brushes
  • smart surface

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