Phosphoinositide 3-kinase and INPP4B in human breast cancer

Micka Claire Bertucci; Christina Anne Mitchell

doi:10.1111/nyas.12036

Phosphoinositide 3-kinase and INPP4B in human breast cancer

Micka Claire Bertucci
, Christina Anne Mitchell

Biochemistry & Molecular Biology

Research output: Contribution to journal › Article › Research › peer-review

44 Citations (Scopus)

Abstract

The PI3K/Akt signaling pathway is frequently increased in many human cancers, including breast cancer. Recent studies have identified INPP4B, which inhibits PI3K signaling, as an emerging tumor suppressor in breast cancer. This short review discusses these issues and the possibility that INPP4B is an important regulator in many cancers.

Original language	English
Pages (from-to)	1 - 5
Number of pages	5
Journal	Annals of the New York Academy of Sciences
Volume	1280
Issue number	1
DOIs	https://doi.org/10.1111/nyas.12036
Publication status	Published - 2013

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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2254950-oaAccepted author manuscript, 156 KB

Cite this

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abstract = "The PI3K/Akt signaling pathway is frequently increased in many human cancers, including breast cancer. Recent studies have identified INPP4B, which inhibits PI3K signaling, as an emerging tumor suppressor in breast cancer. This short review discusses these issues and the possibility that INPP4B is an important regulator in many cancers.",

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Phosphoinositide 3-kinase and INPP4B in human breast cancer

Abstract

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