TY - JOUR
T1 - Phosphodiester cleavage properties of copper(II) complexes of 1,4,7-triazacyclononane ligands bearing single alkyl guanidine pendants
AU - Tjioe, Linda
AU - Joshi, Tanmaya
AU - Forsyth, Craig Macdonald
AU - Moubaraki, Boujemaa
AU - Murray, Keith Spencer
AU - Brugger, Joel
AU - Graham, Bimbil
AU - Spiccia, Leone
PY - 2012
Y1 - 2012
N2 - Three new metal-coordinating ligands, L(1)center dot 4HCl [1-(2-guanidinoethyl)-1,4,7-triazacyclononane tetrahydrochloride], L(2)center dot 4HCl [1-(3-guanidinopropyl)-1,4,7-triazacyclononane tetrahydrochloride], and L(3)center dot 4HCl [1-(4-guanidinobutyl)-1,4,7-triazacyclononane tetrahydrochloride], have been prepared via the selective N-functionalization of 1,4,7-triazacyclononane (tacn) with ethylguanidine, propylguanidine, and butylguanidine pendants, respectively. Reaction of L(1)center dot 4HCl with Cu(ClO(4))(2)center dot 6H(2)O in basic aqueous solution led to the crystallization of a monohydroxo-bridged binuclear copper(II) complex, [Cu(2)L(2)(1)(mu-OH)](ClO(4))(3)center dot H(2)O (Cl), while for L2 and L3, mononuclear complexes of composition [Cu(L(2)H)Cl(2)]Cl center dot(MeOH)(0.5)(H(2)O)(0.5) (C2) and [Cu(L(3)H)Cl(2)]Cl center dot(DMF)(0.5)center dot(H(2)O)(0.5) (C3) were crystallized from methanol and DMF solutions, respectively.
AB - Three new metal-coordinating ligands, L(1)center dot 4HCl [1-(2-guanidinoethyl)-1,4,7-triazacyclononane tetrahydrochloride], L(2)center dot 4HCl [1-(3-guanidinopropyl)-1,4,7-triazacyclononane tetrahydrochloride], and L(3)center dot 4HCl [1-(4-guanidinobutyl)-1,4,7-triazacyclononane tetrahydrochloride], have been prepared via the selective N-functionalization of 1,4,7-triazacyclononane (tacn) with ethylguanidine, propylguanidine, and butylguanidine pendants, respectively. Reaction of L(1)center dot 4HCl with Cu(ClO(4))(2)center dot 6H(2)O in basic aqueous solution led to the crystallization of a monohydroxo-bridged binuclear copper(II) complex, [Cu(2)L(2)(1)(mu-OH)](ClO(4))(3)center dot H(2)O (Cl), while for L2 and L3, mononuclear complexes of composition [Cu(L(2)H)Cl(2)]Cl center dot(MeOH)(0.5)(H(2)O)(0.5) (C2) and [Cu(L(3)H)Cl(2)]Cl center dot(DMF)(0.5)center dot(H(2)O)(0.5) (C3) were crystallized from methanol and DMF solutions, respectively.
UR - http://pubs.acs.org.ezproxy.lib.monash.edu.au/doi/pdf/10.1021/ic2019814
U2 - 10.1021/ic2019814
DO - 10.1021/ic2019814
M3 - Article
SN - 0020-1669
VL - 51
SP - 939
EP - 953
JO - Inorganic Chemistry
JF - Inorganic Chemistry
IS - 2
ER -