Phases of reprogramming

Laurent David, Jose M Polo

Research output: Contribution to journalArticleResearchpeer-review

98 Citations (Scopus)

Abstract

Despite advances in the field of somatic cell reprogramming, an understanding and exploration of the underlying mechanisms governing this process are only recently emerging. It is now increasingly apparent that key sequential events correlate with the reprogramming process; a process previously thought to be random and unpredictable is now looking, to a greater extent, defined and controlled. Herein, we will review the key cellular and molecular events associated with the reprogramming process, giving an integrative and conciliatory view of the different studies addressing the mechanism of nuclear reprogramming.
Original languageEnglish
Pages (from-to)754 - 761
Number of pages8
JournalStem Cell Research
Volume12
Issue number3
DOIs
Publication statusPublished - 2014

Cite this