Abstract
We present the outcomes of combined feasibility studies carried out at Elettra and Australian Synchrotron to evaluate novel protocols for three dimensional (3D) mammographic phase contrast imaging. A custom designed plastic phantom and some tissue samples have been studied at diverse resolution scales and experimental conditions. Several computed tomography (CT) reconstruction algorithms with different pre-processing and post-processing steps have been considered. Special attention was paid to the effect of phase retrieval on the diagnostic value of the reconstructed images. The images were quantitatively evaluated using objective quality indices in comparison with subjective assessments performed by three experienced radiologists and one pathologist. We show that the propagation-based phase-contrast imaging (PBI) leads to substantial improvement to the contrast-to-noise and to the intrinsic quality of the reconstructed CT images compared with conventional techniques as well as to an important reduction of the delivered doses, thus opening the way to clinical implementations.
| Original language | English |
|---|---|
| Title of host publication | Breast Imaging - 13th International Workshop, IWDM 2016, Proceedings |
| Editors | Anders Tingberg, Kristina Lång, Pontus Timberg |
| Publisher | Springer-Verlag London Ltd. |
| Pages | 625-634 |
| Number of pages | 10 |
| Volume | 9699 |
| ISBN (Print) | 9783319415451 |
| DOIs | |
| Publication status | Published - 2016 |
| Event | International Workshop on Digital Mammography 2016 - Malmo, Sweden Duration: 19 Jun 2016 → 22 Jun 2016 Conference number: 13th http://www.springer.com/gp/book/9783319415451 |
Publication series
| Name | Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) |
|---|---|
| Volume | 9699 |
| ISSN (Print) | 03029743 |
| ISSN (Electronic) | 16113349 |
Workshop
| Workshop | International Workshop on Digital Mammography 2016 |
|---|---|
| Abbreviated title | IWDM 2016 |
| Country | Sweden |
| City | Malmo |
| Period | 19/06/16 → 22/06/16 |
| Other | WDM: International Workshop on Digital Mammography Proceedings published in a Spriner book Breast Imaging 13th International Workshop, IWDM 2016, Malmö, Sweden, June 19-22, 2016, Proceedings Editors: Tingberg, Anders, Lång, Kristina, Timberg, Pontus (Eds.) |
| Internet address |
Keywords
- Breast CT
- Computed tomography
- Mammography
- Phase contrast
- Synchrotron radiation
- X-rays
Cite this
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Phase-contrast clinical breast CT : Optimization of imaging setups and reconstruction workflows. / Tromba, Giuliana; Pacilè, Serena; Nesterets, Yakov I.; Brun, Francesco; Dullin, Christian; Dreossi, Diego; Mayo, Sheridan C.; Stevenson, Andrew W.; Pavlov, Konstantin M; Kitchen, Markus J; Thompson, Darren; Brown, Jeremy M C; Lockie, Darren; Tonutti, Maura; Stacul, Fulvio; Zanconati, Fabrizio; Accardo, Agostino; Gureyev, Timur E.
Breast Imaging - 13th International Workshop, IWDM 2016, Proceedings. ed. / Anders Tingberg; Kristina Lång; Pontus Timberg. Vol. 9699 Springer-Verlag London Ltd., 2016. p. 625-634 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 9699).Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › Research › peer-review
TY - GEN
T1 - Phase-contrast clinical breast CT
T2 - Optimization of imaging setups and reconstruction workflows
AU - Tromba, Giuliana
AU - Pacilè, Serena
AU - Nesterets, Yakov I.
AU - Brun, Francesco
AU - Dullin, Christian
AU - Dreossi, Diego
AU - Mayo, Sheridan C.
AU - Stevenson, Andrew W.
AU - Pavlov, Konstantin M
AU - Kitchen, Markus J
AU - Thompson, Darren
AU - Brown, Jeremy M C
AU - Lockie, Darren
AU - Tonutti, Maura
AU - Stacul, Fulvio
AU - Zanconati, Fabrizio
AU - Accardo, Agostino
AU - Gureyev, Timur E
PY - 2016
Y1 - 2016
N2 - We present the outcomes of combined feasibility studies carried out at Elettra and Australian Synchrotron to evaluate novel protocols for three dimensional (3D) mammographic phase contrast imaging. A custom designed plastic phantom and some tissue samples have been studied at diverse resolution scales and experimental conditions. Several computed tomography (CT) reconstruction algorithms with different pre-processing and post-processing steps have been considered. Special attention was paid to the effect of phase retrieval on the diagnostic value of the reconstructed images. The images were quantitatively evaluated using objective quality indices in comparison with subjective assessments performed by three experienced radiologists and one pathologist. We show that the propagation-based phase-contrast imaging (PBI) leads to substantial improvement to the contrast-to-noise and to the intrinsic quality of the reconstructed CT images compared with conventional techniques as well as to an important reduction of the delivered doses, thus opening the way to clinical implementations.
AB - We present the outcomes of combined feasibility studies carried out at Elettra and Australian Synchrotron to evaluate novel protocols for three dimensional (3D) mammographic phase contrast imaging. A custom designed plastic phantom and some tissue samples have been studied at diverse resolution scales and experimental conditions. Several computed tomography (CT) reconstruction algorithms with different pre-processing and post-processing steps have been considered. Special attention was paid to the effect of phase retrieval on the diagnostic value of the reconstructed images. The images were quantitatively evaluated using objective quality indices in comparison with subjective assessments performed by three experienced radiologists and one pathologist. We show that the propagation-based phase-contrast imaging (PBI) leads to substantial improvement to the contrast-to-noise and to the intrinsic quality of the reconstructed CT images compared with conventional techniques as well as to an important reduction of the delivered doses, thus opening the way to clinical implementations.
KW - Breast CT
KW - Computed tomography
KW - Mammography
KW - Phase contrast
KW - Synchrotron radiation
KW - X-rays
UR - http://www.scopus.com/inward/record.url?scp=84977562829&partnerID=8YFLogxK
U2 - 10.1007/978-3-319-41546-8_78
DO - 10.1007/978-3-319-41546-8_78
M3 - Conference Paper
SN - 9783319415451
VL - 9699
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 625
EP - 634
BT - Breast Imaging - 13th International Workshop, IWDM 2016, Proceedings
A2 - Tingberg, Anders
A2 - Lång, Kristina
A2 - Timberg, Pontus
PB - Springer-Verlag London Ltd.
ER -