pH-Responsive, Amphiphilic Core-Shell Supramolecular Polymer Brushes from Cyclic Peptide-Polymer Conjugates

Sophie C. Larnaudie, Johannes C. Brendel, Katrina A. Jolliffe, Sébastien Perrier

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Abstract

The synthesis and self-assembly of pH-responsive, amphiphilic cyclic peptide-polymer conjugates are described. The design relies on the introduction of a poly(2-(diisopropylamino)ethyl methacrylate) (pDPA) block between the cyclic peptide and a hydrophilic block. These conjugates are disassembled and protonated at low pH but assemble into core-shell nanotubes at physiological pH, as determined by a combination of titration experiments and scattering techniques.

Original languageEnglish
Pages (from-to)1347-1351
Number of pages5
JournalACS Macro Letters
Volume6
Issue number12
DOIs
Publication statusPublished - 19 Dec 2017

Cite this

Larnaudie, Sophie C. ; Brendel, Johannes C. ; Jolliffe, Katrina A. ; Perrier, Sébastien. / pH-Responsive, Amphiphilic Core-Shell Supramolecular Polymer Brushes from Cyclic Peptide-Polymer Conjugates. In: ACS Macro Letters. 2017 ; Vol. 6, No. 12. pp. 1347-1351.
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pH-Responsive, Amphiphilic Core-Shell Supramolecular Polymer Brushes from Cyclic Peptide-Polymer Conjugates. / Larnaudie, Sophie C.; Brendel, Johannes C.; Jolliffe, Katrina A.; Perrier, Sébastien.

In: ACS Macro Letters, Vol. 6, No. 12, 19.12.2017, p. 1347-1351.

Research output: Contribution to journalArticleResearchpeer-review

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AU - Perrier, Sébastien

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