PfRH5 as a candidate vaccine for plasmodium falciparum malaria

Damien R Drew; James G Beeson

doi:10.1016/j.pt.2015.02.001

PfRH5 as a candidate vaccine for plasmodium falciparum malaria

Damien R Drew
, James G Beeson

Microbiology

Research output: Contribution to journal › Article › Other

16 Citations (Scopus)

Abstract

PfRH5 has recently emerged as a strong vaccine candidate for Plasmodium falciparum malaria. Antibodies inhibit invasion of erythrocytes by merozoites and blood-stage replication, and PfRH5 is a significant target of acquired human immunity. Recent studies have shown protective efficacy of PfRH5 vaccines in a non-human primate model of malaria.

Original language	English
Pages (from-to)	87 - 88
Number of pages	2
Journal	Trends in Parasitology
Volume	31
Issue number	3
DOIs	https://doi.org/10.1016/j.pt.2015.02.001
Publication status	Published - 2015

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1016/j.pt.2015.02.001

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abstract = "PfRH5 has recently emerged as a strong vaccine candidate for Plasmodium falciparum malaria. Antibodies inhibit invasion of erythrocytes by merozoites and blood-stage replication, and PfRH5 is a significant target of acquired human immunity. Recent studies have shown protective efficacy of PfRH5 vaccines in a non-human primate model of malaria.",

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AU - Drew, Damien R

AU - Beeson, James G

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AB - PfRH5 has recently emerged as a strong vaccine candidate for Plasmodium falciparum malaria. Antibodies inhibit invasion of erythrocytes by merozoites and blood-stage replication, and PfRH5 is a significant target of acquired human immunity. Recent studies have shown protective efficacy of PfRH5 vaccines in a non-human primate model of malaria.

UR - http://www.cell.com/trends/parasitology/pdf/S1471-4922(15)00021-5.pdf

U2 - 10.1016/j.pt.2015.02.001

DO - 10.1016/j.pt.2015.02.001

M3 - Article

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JO - Trends in Parasitology

JF - Trends in Parasitology

IS - 3

ER -

PfRH5 as a candidate vaccine for plasmodium falciparum malaria

Abstract

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