Permissive hypercapnia in acute respiratory distress syndrome - is now the time to get strict?

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Although mechanical ventilation is frequently a life-saving intervention for patients with acute respiratory distress syndrome (ARDS), there is an increasing awareness that mechanical ventilation itself can initiate or exacerbate lung injury. Over the past two decades, there has been a major shift in how we ventilate these patients. Despite the increase in our understanding, the ideal ventilation strategy and the appropriate management of ventilation (control of PaO2) and oxygenation (control of PaO2) for patients with ARDS is still controversial. Many clinicians still aim for physiologically "normala" arterial blood gas parameters and,in this pursuit, may induce additional pulmonary injury, thus increasing morbidity and mortality.
Original languageEnglish
Pages (from-to)142-143
Number of pages2
JournalCritical Care and Resuscitation
Issue number3
Publication statusPublished - 2011

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