Perioperative pulse contour cardiac output analysis in a patient with severe cardiac dysfunction

D. Jones, David A. Story, P. Peyton, R. Bellomo

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)


We describe a patient with severe left ventricular dysfunction simultaneously monitored with pulse contour cardiac output (PiCCO) analysis, a continuous cardiac output pulmonary artery catheter (continuous COPAC) and intraoperative transoesophageal echocardiography (TOE). There was good agreement between cardiac output (CO) measurements obtained by the three techniques prior to cardiopulmonary bypass (CPB). Agreement of CO measurements following CPB was initially poor, but improved following recalibration of PiCCO. PiCCO-derived global end-dia stolic volume index (GEDVI) and cardiac function index (CFI), were assessed as markers of left ventricular preload and myocardial contractility, respectively. GEDVI correlated well with CO in the postoperative period. CFI increased more than two-f old following coronary revascularization and milrinone administration, and there was also a temporal relationship between the CFI and the dose of milrinone in the first 24 hours of treatment. Global end-diastolic volume and cardiac function index may be useful additional measures of left ventricular preload and myocardial contractility in patients with severe left ventricular dysfunction.

Original languageEnglish
Pages (from-to)97-101
Number of pages5
JournalAnaesthesia and Intensive Care
Issue number1
Publication statusPublished - 1 Feb 2006
Externally publishedYes


  • Cardiac function index
  • Cardiac surgery
  • Global end-diastolic volume
  • Haemodynamic monitoring
  • Milrinone
  • PiCCO
  • Pulse contour cardiac output

Cite this